1. Anti-infection
  2. Bacterial

Ampicillin sodium (Synonyms: D-(-)-α-Aminobenzylpenicillin sodium salt)

Cat. No.: HY-B0522A Purity: 98.00%
Handling Instructions

Ampicillin sodium is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.

For research use only. We do not sell to patients.

Ampicillin sodium Chemical Structure

Ampicillin sodium Chemical Structure

CAS No. : 69-52-3

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in Water USD 66 In-stock
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Estimated Time of Arrival: December 31
1 g USD 60 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
5 g USD 180 In-stock
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Estimated Time of Arrival: December 31
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Other Forms of Ampicillin sodium:

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Ampicillin sodium is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.

In Vitro

Ampicillin inhibits the growth of E. coli of swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin was 2.5 uG/mL[1].

In Vivo

Ampicillin is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig[1]. Ampicillin produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood[2]. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with ampicillin significantly reduces medial hippocampal cell death following global forebrain ischemia[3].

Clinical Trial
References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.6926 mL 13.4629 mL 26.9259 mL
5 mM 0.5385 mL 2.6926 mL 5.3852 mL
10 mM 0.2693 mL 1.3463 mL 2.6926 mL
Please refer to the solubility information to select the appropriate solvent.
Animal Administration
[3]

Mice: Ampicillin is dissolved in normal saline. Male C57BL/6 mice were anesthetized with halothane and subjected to bilateral common carotid artery occlusion for 40 min. Before transient forebrain ischemia, ampicillin (200 mg/kg, intraperitoneally [i.p.]) or penicillin G (6,000 U/kg or 20,000 U/kg, i.p.) was administered daily for 5 days. In the control animals, saline was administered at the same volume and time schedule[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
Molecular Weight

371.39

Formula

C₁₆H₁₈N₃NaO₄S

CAS No.

69-52-3

SMILES

[O-]C([[email protected]@H]1N(C2=O)[[email protected]]([[email protected]@H]2NC([[email protected]@H](C3=CC=CC=C3)N)=O)([H])SC1(C)C)=O.[Na+]

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

H2O: ≥ 200 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Purity: 98.00%

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Product Name:
Ampicillin sodium
Cat. No.:
HY-B0522A
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