1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Ampicillin trihydrate

Ampicillin trihydrate  (Synonyms: D-(-)-α-Aminobenzylpenicillin trihydrate)

Cat. No.: HY-B0522B Purity: 99.93%
COA Handling Instructions

Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.

For research use only. We do not sell to patients.

Ampicillin trihydrate Chemical Structure

Ampicillin trihydrate Chemical Structure

CAS No. : 7177-48-2

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Customer Review

Based on 11 publication(s) in Google Scholar

Other Forms of Ampicillin trihydrate:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

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Description

Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.

IC50 & Target

β-lactam

 

In Vitro

Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) inhibits the growth of E. coli of swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin trihydrate is 2.5 uG/mL[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig[1].
Ampicillin trihydrate produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood[2].
Ampicillin trihydrate provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin trihydrate reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with Ampicillin trihydrate significantly reduces medial hippocampal cell death following global forebrain ischemia[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

403.45

Formula

C16H25N3O7S

CAS No.
SMILES

OC([[email protected]@H]1N(C2=O)[[email protected]]([[email protected]@H]2NC([[email protected]@H](C3=CC=CC=C3)N)=O)([H])SC1(C)C)=O.[3H2O]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 4.55 mg/mL (11.28 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4786 mL 12.3931 mL 24.7862 mL
5 mM 0.4957 mL 2.4786 mL 4.9572 mL
10 mM 0.2479 mL 1.2393 mL 2.4786 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Ampicillin trihydrate
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HY-B0522B
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