146426-40-6
146426-40-6
Chemical Structure
Flavopiridol
Synonym(s): HMR-1275; Alvocidib; L86-8275
- CAS No.: 146426-40-6
- Formula:C21H20ClNO5
- Molecular Weight:401.84
IUPAC Name: 2-(2-chlorophenyl)-5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4H-chromen-4-one
InChIKey: BIIVYFLTOXDAOV-YVEFUNNKSA-N
SMILES: O=C1C2=C(C=C(C([C@]3([H])[C@H](O)CN(C)CC3)=C2OC(C4=CC=CC=C4Cl)=C1)O)O
Biological Activity: Flavopiridol (Alvocidib) is a broad spectrum and competitive inhibitor of CDKs, inhibiting CDK1, CDK2, CDK4 with IC50s of 30, 170, 100 nM, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Flavopiridol | 99.68% | Flavopiridol (Alvocidib) is a broad spectrum and competitive inhibitor of CDKs, inhibiting CDK1, CDK2, CDK4 with IC50s of 30, 170, 100 nM, respectively. | ||||||||||||||||||||
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Flavopiridol (Standard) | ≥98% | Flavopiridol (Standard) is the analytical standard of Flavopiridol (HY-10005). This product is intended for research and analytical applications. Flavopiridol (Alvocidib) is a broad spectrum and competitive inhibitor of CDKs, inhibiting CDK1, CDK2, CDK4 with IC50s of 30, 170, 100 nM, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-10006Flavopiridol Hydrochloride -
Similarity Score 0.81
HY-153260TP-1287 -
Similarity Score 0.79
HY-16559ARiviciclib -
Similarity Score 0.78
HY-16559Riviciclib hydrochloride -
Similarity Score 0.69
HY-111356IIIM-290 -
Similarity Score 0.67
HY-119831Rohitukine -
Similarity Score 0.67
HY-12422Voruciclib -
Similarity Score 0.67
HY-12422Crel-(2S,3R)-Voruciclib -
Similarity Score 0.66
HY-12422AVoruciclib hydrochloride -
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