2492423-29-5
Chemical Structure
Molnupiravir
Synonym(s): EIDD-2801; MK-4482
- CAS No.: 2492423-29-5
- Formula:C13H19N3O7
- Molecular Weight:329.31
IUPAC Name: ((2R,3S,4R,5R)-3,4-dihydroxy-5-(4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl isobutyrate
InChIKey: HTNPEHXGEKVIHG-QCNRFFRDSA-N
SMILES: O=C(N([C@@]1([H])[C@H](O)[C@H](O)[C@@]([H])(COC(C(C)C)=O)O1)C=C2)NC2=NO
Biological Activity: Molnupiravir (EIDD-2801) is an orally bioavailable proagent of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Molnupiravir | 99.85% | Molnupiravir (EIDD-2801) is an orally bioavailable proagent of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Molnupiravir (Standard) | ≥98% | Molnupiravir (Standard) is the analytical standard of Molnupiravir. This product is intended for research and analytical applications. Molnupiravir (EIDD-2801) is an orally bioavailable proagent of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Molnupiravir-d7 | 99.86% | Molnupiravir-d7 is the deuterium labeled Molnupiravir. Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.87
HY-178670N-Butyl molnupiravir -
Similarity Score 0.80
HY-125033EIDD-1931 -
Similarity Score 0.74
HY-156656Tirfipiravir -
Similarity Score 0.73
![((3aR,4R,6R,6aR)-6-((E)-4-(Hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl isobutyrate Chemical Structure](//file.medchemexpress.com/product_pic/hy-45219.gif)
HY-45219((3aR,4R,6R,6aR)-6-((E)-4-(Hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl isobutyrate -
Similarity Score 0.72
HY-125033S1EIDD-1931-d2 -
Similarity Score 0.70
HY-1526651-(β-D-Xylofuranosyl)uracil -
Similarity Score 0.70
HY-B1449S1Uridine-13C -
Similarity Score 0.70
HY-B1449S10Uridine-13C5 -
Similarity Score 0.70
HY-W006429L-Uridine -
Explore the MedChemAI to find more analogs
![((3aR,4R,6R,6aR)-6-((E)-4-(Hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl isobutyrate Chemical Structure](http://file.medchemexpress.com/product_pic/hy-45219.gif)
References
- [1]. Sheahan TP, et al. An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice. Sci Transl Med. 2020 Apr 6. pii: eabb5883. [Content Brief]
- [2]. Toots M, et al. Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia. Sci Transl Med. 2019 Oct 23;11(515). pii: eaax5866. [Content Brief]
