1 Result for "

133812-16-5

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "133812-16-5" in MCE Product Catalog:

Cat. No.: HY-W013411
CAS No.: 133812-16-5
Synonyms: (E/Z)-UIC-1005
Target:  

Raf

Research Areas:  

Cancer

(E/Z)-Locostatin ((E/Z)-UIC-1005) is a racemic of Locostatin. Locostatin (UIC-1005) is a potent RKIP inhibitor. Locostatin binds Raf kinase inhibitor RKIP protein and disrupts the interaction of RKIP with Raf-1 kinase and G protein-coupled receptor kinase 2. Locostatin inhibits cell proliferation and migration. Locostatin aggravates thioacetamide (HY-Y0698)-induced acute liver failure in mice .
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