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1364123-68-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1364123-68-1" in MCE Product Catalog:

(R)-(+)-O-Demethylbuchenavianine
(R)-(+)-O-Demethylbuchenavianine
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Cat. No.: HY-N12625
CAS No.: 1364123-68-1
Category:  

Alkaloids Flavonoids Flavones Other Alkaloids Combretaceae Buchenavia macrophylla Spruce ex Eichler Plants

Target:  

CDK DYRK GSK-3

(R)-(+)-O-Demethylbuchenavianine is an inhibitor for Cyclin-dependent kinases (CDK). (R)-(+)-O-Demethylbuchenavianine inhibits CDK1, CDK5, glycogen synthase kinase-3 (GSK3), cdc2-like kinase (CLK1) and dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A), with IC50s of 1.1, 0.95, >10, >10 and >10 μM, respectively .
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