(R)-(+)-O-Demethylbuchenavianine
Based on 1 Customer Validation
(R)-(+)-O-Demethylbuchenavianine is an inhibitor for Cyclin-dependent kinases (CDK). (R)-(+)-O-Demethylbuchenavianine inhibits CDK1, CDK5, glycogen synthase kinase-3 (GSK3), cdc2-like kinase (CLK1) and dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A), with IC50s of 1.1, 0.95, >10, >10 and >10 μM, respectively.
For research use only. We do not sell to patients.
- Purity: 98.67%
- CAS No.: 1364123-68-1
- Formula: C21H21NO4
- Molecular Weight:351.40
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
|
CDK5 0.95 μM (IC50) |
CDK1 1.1 μM (IC50) |
CLK1 |
DYRK1A |
GSK-3 |
Chemical Information
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CAS No. 1364123-68-1
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Appearance Solid
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Molecular Weight 351.40
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Formula C21H21NO4
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Color Off-white to yellow
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SMILES
OC1=CC(O)=C(C(C=C(C2=CC=CC=C2)O3)=O)C3=C1[C@@H]4N(CCCC4)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)