1364123-68-1

(R)-(+)-O-Demethylbuchenavianine Chemical Structure
1364123-68-1

Chemical Structure

(R)-(+)-O-Demethylbuchenavianine

  • CAS No.: 1364123-68-1
  • Formula:C21H21NO4
  • Molecular Weight:351.40

InChIKey: BBZGOLNDVQZCIH-CQSZACIVSA-N

SMILES: OC1=CC(O)=C(C(C=C(C2=CC=CC=C2)O3)=O)C3=C1[C@@H]4N(CCCC4)C

Biological Activity: (R)-(+)-O-Demethylbuchenavianine is an inhibitor for Cyclin-dependent kinases (CDK). (R)-(+)-O-Demethylbuchenavianine inhibits CDK1, CDK5, glycogen synthase kinase-3 (GSK3), cdc2-like kinase (CLK1) and dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A), with IC50s of 1.1, 0.95, >10, >10 and >10 μM, respectively[1].

Cat. No. Product Name Purity Description Pricing
HY-N12625 		(R)-(+)-O-Demethylbuchenavianine 98.67% (R)-(+)-O-Demethylbuchenavianine is an inhibitor for Cyclin-dependent kinases (CDK). (R)-(+)-O-Demethylbuchenavianine inhibits CDK1, CDK5, glycogen synthase kinase-3 (GSK3), cdc2-like kinase (CLK1) and dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A), with IC50s of 1.1, 0.95, >10, >10 and >10 μM, respectively.
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