Buchenavia macrophylla Spruce ex Eichler
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Buchenavia macrophylla Spruce ex Eichler (2)
(S)-(-)-O-Demethylbuchenavianine
Cat. No.: HY-N12625A
CAS No.: 91147-18-1
- Formula: C21H21NO4
- Molecular Weight: 351.40
(R)-(+)-O-Demethylbuchenavianine
- Formula: C21H21NO4
- Molecular Weight: 351.40
(R)-(+)-O-Demethylbuchenavianine is an inhibitor for Cyclin-dependent kinases (CDK). (R)-(+)-O-Demethylbuchenavianine inhibits CDK1, CDK5, glycogen synthase kinase-3 (GSK3), cdc2-like kinase (CLK1) and dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A), with IC50s of 1.1, 0.95, >10, >10 and >10 μM, respectively.
