1 Result for "

144505-58-8

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "144505-58-8" in MCE Product Catalog:

Cat. No.: HY-106975
CAS No.: 144505-58-8
Target:  

Neprilysin

Research Areas:  

Cardiovascular Disease

SCH-42354 is a potent, orally active neutral endopeptidase (NEP) inhibitor, is the pharmacologically active form of the proagent SCH-42495. SCH-42354 inhibits the hydrolysis of NEP to enhance the activity of atrial natriuretic peptide (ANP). SCH-42354 inhibits hydrolysis of leu-enkephalin and ANF with IC50 values of 8.3 nM and 10.0 nM, respectively. SCH-42354 has antihypertensive activity .
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