1 Result for "

1464842-09-8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1464842-09-8" in MCE Product Catalog:

Cat. No.: HY-133016
CAS No.: 1464842-09-8
Purity:  99.36%
Target:  

MetAP

Research Areas:  

Cardiovascular Disease Cancer

M8891 is an orally active, reversible and brain penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor with an IC50 of 54 nM and a Ki of 4.33 nM. M8891 does not inhibit MetAP-1 (IC50>10 µM) . M8891 inhibits growth of primary endothelial cells as well as tumor cells and demonstrates antiangiogenic and antitumoral activity .
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