1 Result for "

147780-50-5

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "147780-50-5" in MCE Product Catalog:

Cat. No.: HY-124626
CAS No.: 147780-50-5
Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

(R)-(+)-Mequitazine is a histamine H1 receptor antagonist that mainly undergoes bio-transformation via human liver microsomes, resulting in hydroxylated and S-oxidized metabolites. (R)-(+)-Mequitazine competitively binds to the H1 receptors in gastrointestinal, vascular, and respiratory effect cells, thus blocking the endogenous activity of histamine. (R)-(+)-Mequitazine has an inhibitory effect on CYP3A-catalyzed midazolam 1’-hydroxylase. (R)-(+)-Mequitazine can be used in the study of various allergic diseases .
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