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2 Results for "
15-Keto latanoprost
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "15-Keto latanoprost" in MCE Product Catalog:
Cat. No.: HY-130395
CAS No.: 135646-98-9
Target:
Research Areas:
15-Keto latanoprost is a metabolite of Latanoprost, which is an ocular hypotensive agent .
Cat. No.: HY-116889
CAS No.: 369585-22-8
Target:
Research Areas:
15-keto Latanoprost is a potential metabolite of latanoprost (HY-B0577) when administered to animals. 15-keto Latanoprost is also one of the common minor impurities found in commercial preparations of the bulk drug compound. Although much less potent that the parent compound latanoprost, 15-keto latanoprost still retains the ability to produce a small but measurable decrease (1 mm Hg) in the intraocular pressure of normal cynomolgus monkeys when administered at a dose of 1 μg/eye.1 15-keto Latanoprost is also a miotic in the normal cat eye, causing an 8 mm Hg reduction in pupillary diameter at 5 μg/eye. Again, this is not as potent as many other F-type prostaglandins; for example, prostaglandin F2α will produce this degree of miosis at a dose of less than 1 μg/eye.
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