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168635-85-6

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1 Results for "168635-85-6" in MCE Product Catalog:

Carcinoembryonic antigen peptide 1
Carcinoembryonic antigen peptide 1
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Cat. No.: HY-P0277
CAS No.: 168635-85-6
Synonyms: CEA peptide
Category:  

Natural Products Endogenous metabolite Disease Research Fields Cancer

Target:  

IFNAR MHC

Carcinoembryonic antigen peptide 1 (CEA peptide) is a 9-amino acid HLA-A0201-binding cytotoxic T lymphocyte (CTL) epitope peptide derived from carcinoembryonic antigen (CEA). The IC50 of Carcinoembryonic antigen peptide 1 binding to HLA-A0201 is 2 μM. Carcinoembryonic antigen peptide 1 binds to HLA-A0201 to form a peptide-MHC I complex, which is recognized by the T cell receptor (TCR) of CAP1-specific CD8 + CTLs, thereby inducing antigen-specific T cell activation, IFN-γ production, and CTL-mediated lysis of target cells. Carcinoembryonic antigen peptide 1 is used in research on CEA-specific CTL responses and colorectal cancer .
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