1 Result for "

188859-65-6

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "188859-65-6" in MCE Product Catalog:

Cat. No.: HY-P10456
CAS No.: 188859-65-6
Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

[Leu144,Arg147]-PLP (139-151) is a mutant peptide fragment of myelin proteolipid protein (PLP), with the tryptophan and histidine at positions 144 and 147 respectively replaced by leucine and arginine. [Leu144,Arg147]-PLP (139-151) also serves as a T cell receptor (TCR) antagonist for encephalitogenic Th1 clones, blocking their activation in vitro. Furthermore, [Leu144,Arg147]-PLP (139-151) can inhibit the development of experimental autoimmune encephalomyelitis (EAE) .
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