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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
100 Results for "
1H-Pyrazole-3,4,5-d3
" in MedChemExpress (MCE) Product Catalog:
Products (100)
100 Results for "1H-Pyrazole-3,4,5-d3" in MCE Product Catalog:
Cat. No.: HY-W779244
CAS No.: 51038-79-0
19
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Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%) .
8
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Danusertib is a pyrrolo-pyrazole and aurora kinase inhibitor with IC50 of 13, 79, and 61 nM for Aurora A, B, and C, respectively.
3
3 Cited Publications
Cat. No.: HY-19408
CAS No.: 1315323-00-2
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Pyr10 is a pyrazole derivative and a selective TRP cation 3 (TRPC3) inhibitor. Pyr10 inhibits Ca 2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells with an IC50 of 0.72 μM (IC50 of 13.08 μM for store operated Ca 2+ entry in BRL-2H3 cells). Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels .
2
2 Cited Publications
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yGsy2p-IN-1 is a potent inhibitor for yeast glycogen synthase 2 (yGsy2p). yGsy2p-IN-1 is a competitive human glycogen synthase 1 (hGYS1) inhibitor with an IC50 of 2.75 μM and a Ki of 1.31 μM for wild-type hGYS1. yGsy2p-IN-H23 a pyrazole inhibitor, is used for glycogen storage diseases (GSDs) .
1
1 Cited Publications
Cat. No.: HY-41514
CAS No.: 1627924-19-9
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3-Iodo-1-tetrahydropyran-2-yl-pyrazole-4-carbaldehyde is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-W017032
CAS No.: 4023-02-3
Cat. No.: HY-W002736
CAS No.: 152120-54-2
Cat. No.: HY-I0308
CAS No.: 761446-44-0
Cat. No.: HY-W001242
CAS No.: 903550-26-5
Cat. No.: HY-I0314
CAS No.: 269410-08-4
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Nifenazone is a pyrazole agent which can be used in the in the treatment of a variety of rheumatic disorders.
Cat. No.: HY-69052
CAS No.: 25016-11-9
Cat. No.: HY-W004212
CAS No.: 52222-73-8
Cat. No.: HY-W003233
CAS No.: 552846-17-0
Cat. No.: HY-W002351
CAS No.: 5744-51-4
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Propyphenazone (4-Isopropylantipyrine) is an orally active nonacidic pyrazole nonsteroidal anti-inflammatory drug (NSAID). Propyphenazone is a weak nonselective COX inhibitor. Propyphenazone has the effect of reducing pain and antipyretic activity with minimal anti-inflammatory activity .
Synonyms: 4-EthoxycarbonylPyrazole
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Phthalazinone pyrazole is a potent, selective, and orally active inhibitor of Aurora-A kinase with an IC50 of 0.031 μM. Phthalazinone pyrazole can arrests mitosis and subsequently inhibit tumor growth via apoptosis of proliferating cells. Phthalazinone pyrazole suppresses the epithelial-mesenchymal transition (EMT) during the differentiation of hepatocyte-like cells (HLCs) from human embryonic stem cells .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
