1 Result for "

2230836-55-0

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2230836-55-0" in MCE Product Catalog:

12
12 Cited Publications
Cat. No.: HY-125817
CAS No.: 2230836-55-0
Purity:  99.95%
Target:  

SOS1 Ras p38 MAPK

Research Areas:  

Cancer

BI-3406 (compound I-6) is an orally active, highly potent and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with an IC50 of 6 nM. BI-3406 potently reduces the formation of GTP-loaded KRAS, and inhibits MAPK pathway signaling. BI-3406 has anticancer activity .
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