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2484862-54-4

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-139617
    Sec61-IN-3

    		Sec61 PD-1/PD-L1 Interleukin Related EGFR Cancer
    Sec61-IN-3 is a Sec61 inhibitor. Sec61-IN-3 shows a significant inhibitory effect on PD-1 related reporter gene cell models (PD1tsGluc) (IC50 = 42 nM), and also has certain inhibitory activity on Her3 (IC50 = 99 nM), IL2 (IC50 = 144 nM) related reporter pathways, but has a relatively weak inhibitory effect on the TNFα (IC50 = 580 nM) pathway. Sec61-IN-3 can be used for cancer research .
    Sec61-IN-3

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