1 Result for "

2488764-06-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2488764-06-1" in MCE Product Catalog:

Cat. No.: HY-156505A
CAS No.: 2488764-06-1
Target:  

iGluR

Research Areas:  

Neurological Disease

R-(+)-EU-1180-453 is a positive allosteric modulator targeting NMDA receptors containing GluN2C and GluN2D subunits, with a pEC50 value of 5.5 for both rat receptor subtypes, and it can cross the blood-brain barrier. R-(+)-EU-1180-453 increases the potency of glutamate, enhances receptor responses to maximally effective concentrations of agonists, and acts only on receptors bound to both co-agonists. R-(+)-EU-1180-453 is applicable to research related to Alzheimer's disease, Parkinson's disease, epilepsy, and neuropathic pain .
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