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251310-57-3

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "251310-57-3" in MCE Product Catalog:

Cat. No.: HY-127024
CAS No.: 251310-57-3
Research Areas:  

Metabolic Disease

Thyroid hormone receptor antagonist (1-850) is a competitive, selective and high-affinity thyroid hormone receptor (TR) antagonist with an IC50 of 1.5 μM for antagonizing the effect of T3 on TR. Thyroid hormone receptor antagonist (1-850) blocks T3-mediated interaction of TRα and TRβ with nuclear receptor coactivator. Thyroid hormone receptor antagonist (1-850) has no effect on the activity of RARα .
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