2 Results for "

2636846-41-6

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "2636846-41-6" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-156633
CAS No.: 2636846-41-6
Purity:  99.78%
Synonyms: PC14586
Target:  

MDM-2/p53

Research Areas:  

Cancer

Rezatapopt (PC14586) is an orally active antineoplastic agent. Rezatapopt binds to a pocket created by the TP53 Y220C mutation. Rezatapopt restores p53 tumor suppressor functions by stabilization of the p53 protein structure. Rezatapopt demonstrates tumor inhibition and regression in mouse models with established human tumor xenografts harboring the TP53 Y220C mutation .
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Cat. No.: HY-156633R
CAS No.: 2636846-41-6
Synonyms: PC14586 (Standard)
Research Areas:  

Cancer

Rezatapopt (Standard) is the analytical standard of Rezatapopt (HY-156633). This product is intended for research and analytical applications. Rezatapopt (PC14586) is an orally active antineoplastic agent. Rezatapopt binds to a pocket created by the TP53 Y220C mutation. Rezatapopt restores p53 tumor suppressor functions by stabilization of the p53 protein structure. Rezatapopt demonstrates tumor inhibition and regression in mouse models with established human tumor xenografts harboring the TP53 Y220C mutation .
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