1 Result for "

2755794-94-4

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2755794-94-4" in MCE Product Catalog:

Cat. No.: HY-162141
CAS No.: 2755794-94-4
Research Areas:  

Cancer

MD102 is an orally active transglutaminase 2 (TG2) inhibitor with an IC50 of 0.35 μM. MD102 binds to the β-sandwich domain of TG2, disrupts the interaction between TG2 and p53, stabilizes p53, and reduces the activity of p-AKT and p-mTOR signaling pathways. MD102 induces cell apoptosis and inhibits tumor growth. MD102 can be used for the research of renal cell carcinoma .
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