1 Result for "

2756323-28-9

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2756323-28-9" in MCE Product Catalog:

Cat. No.: HY-170982
CAS No.: 2756323-28-9
Target:  

PROTACs MEK

Research Areas:  

Cancer

MS910 is a CRBN-recruiting MEK1/2 PROTAC degrader, with a DC50 of 94 nM against MEK1 and 38 nM against MEK2 in SK-MEL-28 cells. MS910 induces the degradation of GSPT1, IKZF1/3 and ZFP91, thereby inhibiting the downstream ERK signaling pathway and cancer cell growth. MS910 is applicable to research related to colorectal cancer and melanoma .
loading...
    loading...