1 Result for "

2762405-17-2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2762405-17-2" in MCE Product Catalog:

Cat. No.: HY-152026
CAS No.: 2762405-17-2
Purity:  99.60%
Target:  

NADPH Oxidase

Research Areas:  

Neurological Disease

NADPH oxidase-IN-1 is an orally active NADPH oxidase (Nox) inhibitor, related with neuronal inflammation. NADPH oxidase-IN-1 can cross the blood-brain barrier (BBB), inhibits Nox2 and Nox4 with IC50s of 1.9 μM and 2.47 μM, respectively. NADPH oxidase-IN-1 suppresses pro-inflammatory cytokines production and LPS-mediated microglial migration, also has in vivo efficacy .
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