1 Result for "

3046228-11-6

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "3046228-11-6" in MCE Product Catalog:

Cat. No.: HY-149091
CAS No.: 3046228-11-6
Purity:  99.68%
Target:  

Histone Demethylase

Research Areas:  

Cancer

KDM5B-IN-4 (compound 11ad) is a lysine demethylase 5B (KDM5B) inhibitor with an IC50 of 0.025 μM KDM5B-IN-4 increases substrate H3K4me1/2/3 level by inhibiting KDM5B in PC-3 cells. KDM5B-IN-4 downregulates PI3K/AKT. KDM5B-IN-4 reduces tumor volume in mice and shows less toxic to organs .
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