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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
7721
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "7721" in MCE Product Catalog:
11
11 Cited Publications
Synonyms: 1-Adamantanamine; 1-Aminoadamantane
Research Areas:
Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
Cat. No.: HY-Z7721
CAS No.: 88475-69-8
Synonyms: (Rac)-TRK-100; (Rac)-ML 1129 sodium
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(Rac)-Beraprost ((Rac)-ML 1129) sodium is a racemic isomer of Beraprost sodium (HY-13569A). Beraprost sodium is an orally active prostacyclin analog that inhibits the release of Ca 2+ from intracellular storage sites by binding to prostacyclin membrane receptors (Prostaglandin Receptor), leading to relaxation of smooth muscle cells and vasodilation. Beraprost sodium has vasodilatory, antiplatelet, and cytoprotective effects, making it promising for research in the field of cardiovascular diseases, such as thromboangiitis obliterans and atherosclerosis .
Cat. No.: HY-P11308
CAS No.: 1421680-54-7
Cat. No.: HY-B0402B
CAS No.: 31377-23-8
Synonyms: 1-Adamantanamine sulfate; 1-Aminoadamantane sulfate
Research Areas:
Amantadine (1-Adamantanamine) sulfate is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine sulfate inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine sulfate also has anti-orthopoxvirus and anticancer activity. Amantadine sulfate can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
Cat. No.: HY-N7022
CAS No.: 158511-59-2
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Cat. No.: HY-N4048
CAS No.: 133453-58-4
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Alkaloids Piperidine Alkaloids Dicranostigma leptopodum (Maxim.) Fedde Plants Disease Research Fields Papaveraceae Cancer
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Cat. No.: HY-N16067
CAS No.: 1442381-95-4
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Cat. No.: HY-178918
CAS No.: 1282141-20-1
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XZA-1 is a 3-hydroxyacyl-coenzyme A dehydrogenase (HADH) activator. XZA-1 increases the intracellular level of acetoacetyl-CoA, which in turn induces acetoacetylation modification of Chromobox Protein Homolog 4 (CBX4) at lysine 106 (K106). XZA-1 exhibits antitumor effects in a xenograft model of human hepatocellular carcinoma SMMC7721 cells overexpressing CBX4. XZA-1 can be used for the study of hepatocellular carcinoma .
Cat. No.: HY-N3722
CAS No.: 123497-84-7
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Cat. No.: HY-N10877
CAS No.: 1461760-59-7
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Cat. No.: HY-N7022R
CAS No.: 158511-59-2
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Cat. No.: HY-160064
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SW1-A aptamer sodium is an optimized aptamer based on SW1 aptamer (HY-160063) that specifically targets liver cancer SMMC-7721 cells (Kd: 133.73 nM). SW1-A aptamer maintains strong affinity to liver cancer tissues and cells .
Cat. No.: HY-160063
Research Areas:
SW1 aptamer sodium is a high-affinity DNA aptamer (Kd: 123.62 nM) that targets liver cancer SMMC-7721 cells and targets intracellular components within the nucleus. SW1 aptamer sodium can also identify various other types of cancer cells and tissues, serving as an effective molecular probe for clinical cancer diagnosis .
Cat. No.: HY-N10876
CAS No.: 863301-69-3
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Cat. No.: HY-N3210
CAS No.: 60048-88-6
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Cat. No.: HY-D1267
CAS No.: 1613402-20-2
PAO-Nap is the modified PAO attached a naphthalimide fluorophore using aminocaproic acid as a linker. PAO induces oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase .
Cat. No.: HY-N8508
CAS No.: 910292-40-9
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Cat. No.: HY-145290
CAS No.: 2968315-02-6
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CPT-Se3, a selenoproagent of Camptothecin (CPT), shows improved potency in killing cancer cells and inhibiting tumor growth. CPT–Se3 decreases the GSH/GSSG ratio and total thiols, elevates the ROS level in Hep G2 cells, and eventually induces apoptosis of cancer cells. CPT-Se3 shows cytotoxicity against HeLa, Hep G2, A549, and SMMC-7721 cells (IC50= 2.19-4.7 μM) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
