1 Result for "

A 889425

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "A 889425" in MCE Product Catalog:

Cat. No.: HY-133166
CAS No.: 1072921-02-8
Target:  

TRP Channel

Research Areas:  

Neurological Disease

A-889425 is an oral active selective TRPV1 receptor antagonist with the with an IC50 of 335 nM (rat) and 34 nM (human). A-889425 has good penetration into the CNS and reduces mechanical allodynia and spinal neuron responses to mechanical stimulation of Complete Freund's adjuvant (HY-153808)-inflamed rat hind paws .
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