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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
ADC linker-drug conjugates
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "ADC linker-drug conjugates" in MCE Product Catalog:
Cat. No.: HY-160967
CAS No.: 2928560-25-0
Research Areas:
MC-GGFG-PAB-Exatecan is a linker-drug conjugate, consisting of the MC-GGFG-PAB (HY-136432) linker and the Topoisomerase I inhibitor Exatecan (HY-13631). MC-GGFG-PAB-Exatecan can be used to synthesize antibody-drug conjugates (ADCs). MC-GGFG-PAB-Exatecan applies to cancer research .
Cat. No.: HY-164296
CAS No.: 2760408-63-5
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SMP-96745 is a dual-reagent linkage assembly unit that can conjugate with targeting moieties to form dual-reagent targeted linker-drug conjugates, such as ADC. SMP-96745 is applicable to the research of breast adenocarcinoma and gastric cancer .
Cat. No.: HY-164310
CAS No.: 2862795-63-7
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TCO-PEG3-Glu-Val-Cit-PABC-MMAF is a linker-drug conjugate, which is consisted of a click pair TCO, a spacer PEG, a cleavable linker Glu-Val-Cit, a PBAC group and a cytotoxin MMAF (HY-15579). TCO-PEG3-Glu-Val-Cit-PABC-MMAF can be used for synthesis of dual drug ADC .
Cat. No.: HY-160683
CAS No.: 2907719-55-3
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MC-Gly-Gly-Phe-Gly-NH-CH2-O-amide-Eribulin (Compound 7) can be used as a linker-drug intermediate for the synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-179254
CAS No.: 2750622-90-1
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Mal-L-Dap (Boc, t-BuOAc) - Pfp Ester (Compound M3) is a highly active linker precursor that can be used to form antibody-drug conjugates (ADCs) .
Cat. No.: HY-160969
CAS No.: 1642147-15-6
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Spiro-duocarmycin is a DNA minor groove N3-adenine alkylating agent. Spiro-duocarmycin exerts cytotoxic effects via DNA alkylation. Spiro-duocarmycin is the active spirocyclized form of seco-DUBA, which is incorporated as an inactive prodrug into the linker-drug construct of antibody-drug conjugates (ADCs). DUBA serves as an ADC payload that can be conjugated with monoclonal antibodies to synthesize antibody-drug conjugates (ADCs) .
Cat. No.: HY-187637
CAS No.: 1918106-06-5
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Research Areas:
Govitecan is a topoisomerase I inhibitor and also a linker-payload compound for antibody-drug conjugates (ADCs), with SN-38 as its active component. Govitecan serves as the linker-drug moiety of ADCs targeting CDH17-expressing cancer cells. Govitecan acts as the cytotoxic payload component of ADCs targeting Trop-2. Govitecan can be used in research related to colorectal cancer, gastric cancer, pancreatic cancer, liver cancer, metastatic triple-negative breast cancer, and other conditions .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
