1642147-15-6
1642147-15-6
Chemical Structure
DUBA
- CAS No.: 1642147-15-6
- Formula:C29H22N4O4
- Molecular Weight:490.51
IUPAC Name: 4-hydroxy-N-(2-((8bR,9aS)-8-methyl-4-oxo-2,4,9,9a-tetrahydro-1H-benzo[e]cyclopropa[c]indole-2-carbonyl)imidazo[1,2-a]pyridin-6-yl)benzamide
InChIKey: MWZTVLNYXAKUKY-LBEKAKSKSA-N
SMILES: O=C(C1=CN2C(C=CC(NC(C3=CC=C(C=C3)O)=O)=C2)=N1)N4C([C@@]5(C6=C(C)C=CC=C67)[C@](C4)([H])C5)=CC7=O
Biological Activity: DUBA is a toxin compound that acts on DNA, exhibiting alkylating activity. DUBA is an ADC payload that can be coupled with monoclonal antibodies to synthesize antibody-drug conjugates (ADCs)[1].
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DUBA | DUBA is a toxin compound that acts on DNA, exhibiting alkylating activity. DUBA is an ADC payload that can be coupled with monoclonal antibodies to synthesize antibody-drug conjugates (ADCs). | |||||||||||||||||||||
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References
Keywords
