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15 Results for "
AHR-IN-1
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "AHR-IN-1" in MCE Product Catalog:
Cat. No.: HY-169753
CAS No.: 2247951-12-6
Target:
Research Areas:
AHR-IN-1 (1-103) is an aryl hydrocarbon receptor (AHR) inhibitor with IC50 < 0.5 μM [1].
2
2 Cited Publications
Synonyms: AHR antagonist 1
Target:
Research Areas:
BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC50 of 39.9 nM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses [1].
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1 Cited Publications
Cat. No.: HY-W015273A
CAS No.: 29953-71-7
Target:
Research Areas:
β-NF-JQ1 is a BRD2/3/4 PROTAC degrader. β-NF-JQ1 recruits the AhR E3 ligase complex to BRD2, BRD3 and BRD4, induces AhR-BRD interaction, and mediates AhR-dependent degradation through the proximity effect between the target protein and AhR. β-NF-JQ1 acts as an antiproliferative and cytotoxic agent that induces anticancer activity associated with BRD protein knockdown. β-NF-JQ1 can be used for research on breast cancer and neuroblastoma [1] .
Cat. No.: HY-N10123
CAS No.: 951207-88-8
Target:
Target:
Research Areas:
Sulazepam, a benzodiazepine, is a selective ovarian cancer G protein-coupled receptor (OGR1) agonist. Sulazepam has anticonvulsive action and has the potential for airway hyperresponsiveness (AHR) research .
Cat. No.: HY-W015273AR
CAS No.: 29953-71-7
Cat. No.: HY-W012278
CAS No.: 56-55-3
Synonyms: Tetraphene
Research Areas:
Benz[a]anthracene (Tetraphene) is a polycyclic aromatic hydrocarbon pollutant and also a ligand of aryl hydrocarbon receptor 2 (AHR2), with a pIC50 of 7.319. Benz[a]anthracene can be detected in spruce needles near aluminum smelters. Exposure to Benz[a]anthracene during zebrafish embryonic stage activates the AHR-CYP1A signaling pathway and induces AHR2 expression, leading to social behavioral deficits that persist into adulthood, accompanied by impaired neuro-immune interaction, while anxiety levels remain unaffected. Benz[a]anthracene can be used in studies related to PAH environmental toxicology, developmental neurotoxicity and biodegradation [1] .
Cat. No.: HY-N6264
CAS No.: 264624-38-6
Category:
Triterpenes Terpenoids Ranunculaceae Metabolic Disease Plants Cimicifuga foetida Linn. Cimicifuga racemosa (L.) Nutt. Disease Research Fields
Target:
Cat. No.: HY-135671
CAS No.: 118174-38-2
Research Areas:
AhR modulator-1 (compound 6-MCDF) is a selective and orally active aryl hydrocarbon receptor (AhR) modulator. AhR modulator-1 inhibits metastasis, in part, by inhibiting prostatic VEGF production prior to tumor formation. AhR modulator-1 also possess anti-estrogenic properties in rat uterus [1].
Cat. No.: HY-118792
CAS No.: 352346-46-4
Target:
Research Areas:
AHR activator 1 is an aryl hydrocarbon receptor activator with activity regulating fibroblast growth factor-2 (FGF2)-induced branching morphogenesis. AHR activator 1 prevents the formation of cellular branches by inhibiting AHR signaling. AHR activator 1 also associates with adhesion of dissociated linkers, suggesting the importance of dissociated linkers in the inhibition of branching by AHR agonists. Studies of AHR activator 1 reveal its functional role in mammary gland morphogenesis and play a role in inhibiting FGF-induced invasion [1].
Cat. No.: HY-N6264R
CAS No.: 264624-38-6
Cat. No.: HY-W012278S
CAS No.: 1718-53-2
Synonyms: Tetraphene-d12
Research Areas:
Benz[a]anthracene-d12 (Tetraphene-d12) is the deuterated-labeled Benz[a]anthracene (HY-W012278). Benz[a]anthracene (Tetraphene) is a polycyclic aromatic hydrocarbon pollutant and also a ligand of aryl hydrocarbon receptor 2 (AHR2), with a pIC50 of 7.319. Benz[a]anthracene can be detected in spruce needles near aluminum smelters. Exposure to Benz[a]anthracene during zebrafish embryonic stage activates the AHR-CYP1A signaling pathway and induces AHR2 expression, leading to social behavioral deficits that persist into adulthood, accompanied by impaired neuro-immune interaction, while anxiety levels remain unaffected. Benz[a]anthracene can be used in studies related to PAH environmental toxicology, developmental neurotoxicity and biodegradation [1] .
Cat. No.: HY-105791R
CAS No.: 2898-13-7
Target:
Research Areas:
Sulazepam (Standard) is the analytical standard of Sulazepam (HY-105791). This product is intended for research and analytical applications. Sulazepam, a benzodiazepine, is a selective ovarian cancer G protein-coupled receptor (OGR1) agonist. Sulazepam has anticonvulsive action and has the potential for airway hyperresponsiveness (AHR) research .
Cat. No.: HY-111449R
CAS No.: 2162982-11-6
Synonyms: AHR antagonist 1 (Standard)
Research Areas:
BAY-218 (Standard) is the analytical standard of BAY-218 (HY-111449). This product is intended for research and analytical applications. BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC50 of 39.9 nM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
