352346-46-4
Chemical Structure
AHR activator 1
- CAS No.: 352346-46-4
- Formula:C14H8Cl2N2O
- Molecular Weight:291.13
IUPAC Name: 5-(2,4-dichlorophenyl)-3-phenyl-1,2,4-oxadiazole
InChIKey: WMJVJVBCUBCALD-UHFFFAOYSA-N
SMILES: ClC1=CC=C(C(Cl)=C1)C2=NC(C3=CC=CC=C3)=NO2
Biological Activity: AHR activator 1 is an aryl hydrocarbon receptor activator with activity regulating fibroblast growth factor-2 (FGF2)-induced branching morphogenesis. AHR activator 1 prevents the formation of cellular branches by inhibiting AHR signaling. AHR activator 1 also associates with adhesion of dissociated linkers, suggesting the importance of dissociated linkers in the inhibition of branching by AHR agonists. Studies of AHR activator 1 reveal its functional role in mammary gland morphogenesis and play a role in inhibiting FGF-induced invasion[1].
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AHR activator 1 | AHR activator 1 is an aryl hydrocarbon receptor activator with activity regulating fibroblast growth factor-2 (FGF2)-induced branching morphogenesis. AHR activator 1 prevents the formation of cellular branches by inhibiting AHR signaling. AHR activator 1 also associates with adhesion of dissociated linkers, suggesting the importance of dissociated linkers in the inhibition of branching by AHR agonists. Studies of AHR activator 1 reveal its functional role in mammary gland morphogenesis and play a role in inhibiting FGF-induced invasion. | |||||||||||||||||||||
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