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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
AKR1B10
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "AKR1B10" in MCE Product Catalog:
3
Target:
Research Areas:
Fidarestat (SNK 860) is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease.
Target:
Research Areas:
AKR1B10-IN-1 is a potent inhibitor of AKR1B10 (Aldo-Keto Reductase 1B10) with an IC50 of 3.5 nM. AKR1B10-IN-1 suppresses proliferation, metastasis, and Cisplatin (CDDP) resistance of lung cancer cells .
Cat. No.: HY-RS00533
Target:
Research Areas:
AKR1B10 Human Pre-designed siRNA Set A contains three designed siRNAs for AKR1B10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W040265
CAS No.: 91-40-7
Synonyms: N-Phenylanthranilic acid
Target:
Research Areas:
Fenamic acid (N-Phenylanthranilic acid, NPAA) is an orally active chloride channel blocker. Fenamic acid is the basic constituent of non-steroidal anti-inflammatory agents (NSAIA), and derives into mefenamic, tofenacin, flufenac acid and melofenac acid. Fenamic acid also acts as antibacterial and analgesic agent - .
Cat. No.: HY-RS17238
Target:
Research Areas:
Akr1b10 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Akr1b10 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23692
Target:
Research Areas:
Akr1b10 Rat Pre-designed siRNA Set A contains three designed siRNAs for Akr1b10 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-122177
CAS No.: 314297-32-0
Target:
Research Areas:
MK181 is an aldose reductase (AR) inhibitor with IC50s of 0.71 μM and 4.5 μM for aldose reductase and AKR1B10, respectively. MK181 can bind into the external loop A subpocket of AKR1B10 .
Cat. No.: HY-168526
Target:
Research Areas:
Keap1-Nrf2-IN-24 (compound 57) is a potent Keap1-Nrf2 inhibitor with a Ki value of 13 nM. Keap1-Nrf2-IN-24 increases the protein expression of TRXR1 and NQO1. Keap1-Nrf2-IN-24 increases the AKR1B10 mRNA expression. Keap1-Nrf2-IN-24 shows good metabolic stability .
Cat. No.: HY-105185R
CAS No.: 136087-85-9
Synonyms: SNK 860 (Standard)
Target:
Research Areas:
Fidarestat (Standard) is the analytical standard of Fidarestat (HY-105185). This product is intended for research and analytical applications. Fidarestat (SNK 860) is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease.
Cat. No.: HY-P81368A
Synonyms: AKR1B10; AKR1B11; Aldo-keto reductase family 1 member B10; ARL-1; Aldose reductase-like; Aldose reductase-related protein (ARP; hARP); Small intestine reductase (SI reductase)
Cat. No.: HY-P701972
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AKR1B10; HSI; Prev. AKR1B11; Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase); ARL-1; Aldose Reductase-Like Peptide; Aldose Reductase-Related Protein; Aldose Reductase-Like 1; Small Intestine Reductase; SI Reductase; AKR1B12; HARP; ALDRLn; ARP
Species:
Human
Source:
E. coli
Cat. No.: HY-P701973
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AKR1B10; HSI; Prev. AKR1B11; Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase); ARL-1; Aldose Reductase-Like Peptide; Aldose Reductase-Related Protein; Aldose Reductase-Like 1; Small Intestine Reductase; SI Reductase; AKR1B12; HARP; ALDRLn; ARP
Species:
Human
Source:
E. coli
Cat. No.: HY-W040265R
CAS No.: 91-40-7
Synonyms: N-Phenylanthranilic acid (Standard)
Target:
Research Areas:
Fenamic acid (N-Phenylanthranilic acid, NPAA) is an orally active chloride channel blocker. Fenamic acid is the basic constituent of non-steroidal anti-inflammatory agents (NSAIA), and derives into mefenamic, tofenacin, flufenac acid and melofenac acid. Fenamic acid also acts as antibacterial and analgesic agent - .
Cat. No.: HY-185414
CAS No.: 2724919-70-2
Target:
Research Areas:
KB05-Biotin is streptavidin-conjugated KB05 (HY-149461) that retains the site-specific cysteine covalent reactivity of KB05, enabling specific detection of target proteins via the biotin-streptavidin system. KB05-Biotin serves as a site-specific probe in ELISA-ABPP assays for screening electrophilic small molecules that bind to scout fragment-sensitive cysteines on target proteins in cell lysates, without the need for protein purification .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
