136087-85-9
136087-85-9
Chemical Structure
Fidarestat
Synonym(s): SNK 860
- CAS No.: 136087-85-9
- Formula:C12H10FN3O4
- Molecular Weight:279.22
IUPAC Name: (2S,4S)-6-fluoro-2',5'-dioxospiro[chromane-4,4'-imidazolidine]-2-carboxamide
InChIKey: WAAPEIZFCHNLKK-UFBFGSQYSA-N
SMILES: O=C1NC(N[C@@]12C3=C(C=CC(F)=C3)O[C@H](C(N)=O)C2)=O
Biological Activity: Fidarestat (SNK 860) is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Fidarestat | 99.63% | Fidarestat (SNK 860) is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease. | ||||||||||||||||||||
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Fidarestat (Standard) | ≥98% | Fidarestat (Standard) is the analytical standard of Fidarestat (HY-105185). This product is intended for research and analytical applications. Fidarestat (SNK 860) is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease. | ||||||||||||||||||||
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Keywords
