1 Result for "

AMG-510 (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AMG-510 (Standard)" in MCE Product Catalog:

Cat. No.: HY-114277R
CAS No.: 2296729-00-3
Synonyms: AMG-510 (Standard)
Target:  

Ras Reference Standards

Research Areas:  

Cancer

Sotorasib (Standard) is the analytical standard of Sotorasib. This product is intended for research and analytical applications. Sotorasib (AMG-510) is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. Sotorasib leads to the regression of KRAS G12C‑mutated locally advanced or metastatic non‑small cell lung cancer (NSCLC) .
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