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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
Ai Inhibitors
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "Ai Inhibitors" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-16786
CAS No.: 1256094-72-0
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AI-10-49 is an inhibitor of leukemic oncoprotein CBFβ-SMHHC. AI-10-49 inhibits the binding of CBFβ-SMMHCto the RUNX1 Runt domain with IC50 value of 0.26 μM. AI-10-49 can be used for the research of leukemia .
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Synonyms: GDP sodium, Type I, 96% (HPLC)
Cat. No.: HY-145001
Purity: 99.69%
Research Areas:
20-HC-Me-Pyrrolidine (compound AI-3d) is a potent Aster protein inhibitor with IC50s of 0.11 μM, 0.06 μM, and 0.71 μM for Aster-A, Aster-B, and Aster-C, respectively. 20-HC-Me-Pyrrolidine blocks the ability of Asters to bind and transfer cholesterol. 20-HC-Me-Pyrrolidine also inhibits the movement of low-density lipoprotein (LDL) cholesterol to the endoplasmic reticulum (ER) .
Cat. No.: HY-175641
CAS No.: 3050609-32-7
HPPD-IN-6 (Compound IIy) is a HPPD inhibitor with high rice selectivity. HPPD-IN-6 has potent herbicidal activities against Echinochloa crus-galli and Leymus chinensis, including the herbicide-resistant biotypes with EC50s of 19.62-33.26 g of ai/ha. HPPD-IN-6 effectively controls the weeds in rice fields at 90-150 g of ai/ha. HPPD-IN-6 can be used for the development of herbicide .
Cat. No.: HY-145360
CAS No.: 2100133-77-3
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eIF4A3-IN-6 is a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII. eIF4A3-IN-6 has the potential for the research of eIF4A dependent diseases, including the research of cancer (extracted from patent US20170145026A1) .
Cat. No.: HY-179286
CAS No.: 3070057-48-3
DHAD-IN-2 (compound 6ag) is a potent dihydroxy acid dehydratase (DHAD) inhibitor with a KD of 20 μM. DHAD-IN-2 demonstrates over 85% control effectiveness against Eclipta prostrata, Amaranthus retroflexus, and Setaria viridis at a dosage of 150 g ai/ha, while also showing safety for rice. DHAD-IN-2 can be used for herbicide research .
Cat. No.: HY-168914
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A181 (AI-181) is a DENV-2 inhibitor. A181 can be used for anti-dengue studies .
Cat. No.: HY-145462
CAS No.: 1400974-23-3
N-cis-octadec-9Z-enoyl-L-Homoserine lactone is a potent inhibitor of AhyI. AhyI (expressing acylhomoserine lactone) is responsible for the biosynthesis of autoinducer-1 (AI-1), commonly referred to as a quorum sensing (QS) signaling molecule, which plays an essential role in bacterial communication. N-cis-octadec-9Z-enoyl-L-Homoserine lactone is a competitive inhibitor of AI-1 biosynthesis .
Cat. No.: HY-N14258
CAS No.: 98474-20-5
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Cat. No.: HY-N14259
CAS No.: 98495-38-6
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Cat. No.: HY-178781
Antibacterial agent 297 (Compound A40), an antibacterial agent, is a Lsrk inhibitor (IC50: 0.40 μM; KD: 3.79 μM). Antibacterial agent 297 inhibits biofilm formation and bacterial motility and changes biofilm morphology through AI-2 QS inhibition rather than direct antibacterial effects. Antibacterial agent 297 has favorable oral PK properties .
Cat. No.: HY-129206
CAS No.: 65049-45-8
Synonyms: RU-24476
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Locicortolone (RU-24476) is a synthetic steroid compound. Locicortolone inhibits Angiotensin I (AI) induced pressor response. Locicortolone can be used in antihypertensive studies .
Cat. No.: HY-P2605
CAS No.: 117620-76-5
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Cat. No.: HY-RI01642A
hsa-miR-548ai antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
Cat. No.: HY-179111
CAS No.: 3034320-17-4
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HPK1-IN-64 is a potent, selective, and orally active HPK1 inhibitor with an IC50 value of 1.9 nM. HPK1-IN-64 exhibits selectivity exceeding 100-fold, 80-fold, 300-fold, and 350-fold against off-target kinases such as GLK, MAP4K5, TBK1, and TNIK, respectively. HPK1-IN-64 inhibits SLP76 protein phosphorylation and IL-2 secretion. HPK1-IN-64 may be used in cancer research, such as for colorectal cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
