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AI-10-104 is an inhibitor for runt-related transcription factor (RUNX), which enhances the cytotoxicity in myeloma cells.

For research use only. We do not sell to patients.

AI-10-104 Chemical Structure

AI-10-104 Chemical Structure

CAS No. : 1881276-00-1

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AI-10-104 Related Antibodies

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Description

AI-10-104 is an inhibitor for runt-related transcription factor (RUNX), which enhances the cytotoxicity in myeloma cells[1].

In Vitro

AI-10-104 (0-10 μM) inhibits the RUNX through dissociation of RUNXs-IKZFs complex, enhances the anti-proliferative effect of lenalidomide and its cytotoxicity in myeloma cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

AI-10-104 Related Antibodies

Western Blot Analysis[1]

Cell Line: HEK293T
Concentration: 0-10 μM
Incubation Time:
Result: Decreased levels of IKZF3 and CBFβ.

Cell Proliferation Assay[1]

Cell Line: OPM-1 cells, KMS-11 and U266 cells
Concentration: 1 μM
Incubation Time:
Result: Maintained the cell viability, inhibited proliferation of OPM-1 cells in a moderate effect.
Molecular Weight

309.24

Formula

C14H10F3N3O2
CAS No.
SMILES

FC(F)(F)OC1=CC=C2N=C(C3=NC=CC=C3OC)NC2=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AI-10-104 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AI-10-1041881276-00-1Othersmultiple myelomaOPM-1KMS-11U266HEK293TInhibitorinhibitorinhibit

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AI-10-104
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HY-122657
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