22 Results for "

Anti-CD3 antibody

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "Anti-CD3 antibody" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-K0353

MCE Human CD3/CD28 T Cell Activation Magnetic Beads are based on the two important co-stimulatory signals, without relying on feeder cells (antigen-presenting cells) or antigens, CD3 and CD28, without relying on feeder cells (antigen-presenting cells) or antigens, enabling simple and rapid T cell activation.

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1
1 Cited Publications
Cat. No.: HY-P99592
CAS No.: 1005198-65-1
Synonyms: AMG 110
Target:  

CD3

Research Areas:  

Cancer

Solitomab (AMG 110) is a bispecific anti-CD3 and anti-epithelial-cell-adhesion-molecule (EpCAM) antibody. Solitomab can be used for the research of primary uterine and ovarian carcinosarcoma cancer .
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Cat. No.: HY-P990864

Target:  

CD3

Research Areas:  

Inflammation/Immunology

Anti-CD3 Antibody (OKT-3) is a kind of mouse IgG2a κ antibody inhibitor, targeting to human CD3. Anti-CD3 Antibody (OKT-3) decreases T cells. Anti-CD3 Antibody (OKT-3) can be used for the research of immunology, such as graft-versus-host disease .
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Cat. No.: HY-P99909
CAS No.: 2408850-14-4
Synonyms: PF-06863135; RN-613

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Elranatamab (PF-06863135) is an anti-CD3E/TNFRSF17 human IgG2κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-P99332
CAS No.: 219716-33-3
Synonyms: Anti-Human CD3E Recombinant Antibody; HuM291

Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Visilizumab (Anti-Human CD3E Recombinant Antibody) is a humanized low-Fc receptor binding anti-CD3 monoclonal IgG2 antibody. Visilizumab can be used for ulcerative colitis and Crohn's disease research .
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Cat. No.: HY-P99199
CAS No.: 946415-64-1
Synonyms: NI-0401

Target:  

CD3

Foralumab (NI-0401) is a potent, orally active human monoclonal antibody targeting the CD3. Foralumab modulates immune responses by human cells in NSG mice that were reconstituted with human hematopoietic stem cells .
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Cat. No.: HY-P99418
CAS No.: 2314491-93-3
Synonyms: AMG-160

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Acapatamab (AMG-160) is an anti-CD3E/FOLH1 monoclonal antibody .
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Cat. No.: HY-136427
CAS No.: 79220-94-3
Purity:  98.08%
KRM-III is an orally active TCR inhibitor and NFAT inhibitor with an IC50 of 5 μM against NFAT. KRM-III has no effect on the activation of nuclear factor-κB. KRM-III inhibits T cell proliferation induced by T cell antigen receptor stimulation. KRM-III abrogates anti-CD3 antibody-induced cell activation in vivo. KRM-III reduces paw pad swelling in delayed-type hypersensitivity induced by Bovine serum albumin (HY-D0842). KRM-III alleviates the severity of experimental autoimmune encephalomyelitis (EAE) in mice. KRM-III can be used in studies related to experimental autoimmune encephalomyelitis .
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Cat. No.: HY-D2171
AF488 DBCO is a fluorescent dye and also a click chemistry reagent that can label azide-containing biomolecules. AF488 DBCO mediates the coupling reaction with azide-modified 2'-OMe RNA oligonucleotides. DBCO is a bioorthogonal partner of azides and enables covalent coupling without copper (Ex/Em = 470/520 nm) .
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Cat. No.: HY-P99912
CAS No.: 2250261-27-7
Synonyms: AMG-673

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Emerfetamab is an anti-CD3E/CD33 monoclonal antibody .
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Cat. No.: HY-P991842
Anti-CD3 Antibody (UCHT-1) is an antibody targeting CD3. Anti-CD3 Antibody (UCHT-1) activates the phospholipase C and phosphatidylinositol 3-kinase (PI3K) signaling pathways, elevates intracellular calcium levels, regulates the T3 epitope, and triggers T lymphocyte proliferation. Anti-CD3 Antibody (UCHT-1) also inhibits lymphocyte proliferation, abolishes IL-2 production, and blocks the expression of IL-2 receptors. Anti-CD3 Antibody (UCHT-1) is applicable to research related to graft-versus-host disease, acute myeloid leukemia, and B-cell acute lymphoblastic leukemia .
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Cat. No.: HY-P991209
CAS No.: 2694723-68-5
Synonyms: GNC-035

Target:  

ROR CD3 PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

Nebratamig (GNC-035) is an anti-ROR1/anti-CD3/anti-PD-L1/anti-4-1BB tetra-specific antibody with potential immunostimulatory and antineoplastic activities .
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Cat. No.: HY-P990714
CAS No.: 2750126-32-8

Target:  

CD3

Research Areas:  

Inflammation/Immunology

Obertamig is an engineered, humanized, anti-CD3E/HLA-G monoclonal antibody with humanized CH2-CH3 modifications and consists of half immunoglobulin IgG1 λ2 and a single-chain variable fragment (scFv) .
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Cat. No.: HY-P99837
CAS No.: 2367001-71-4
Synonyms: SPV-T3a

Target:  

CD3

Research Areas:  

Infection

Dafsolimab (SPV-T3a) is a Mouse IgG2b monoclonal antibody (anti-CD3). Dafsolimab can induce cell death through modulation and activation of the CD3/T cell receptor complex. Dafsolimab can be used for the research of graft-versus-host disease (GVHD) .
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Cat. No.: HY-P990698
CAS No.: 2599198-83-9

Target:  

PD-1/PD-L1 EGFR

Research Areas:  

Inflammation/Immunology

Umizortamig is an anti-CD3E/EGFR/TNFRSF9/PD-L1/CD3G monoclonal antibody .
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Cat. No.: HY-P991406

Target:  

TNF Receptor

Research Areas:  

Cancer

MK-1248 is a human IgG4 monoclonal antibody (mAb) targeting TNFSF18. MK-1248 enhances the proliferative response of tumor-infiltrating lymphocytes to anti-CD3 stimulation and promotes the production of anti-tumor-associated regulatory cytokines. MK-1248 can be used in solid tumors research .
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Cat. No.: HY-P990692
CAS No.: 2412587-62-1
Synonyms: JNJ-70218902; JNJ-902

Target:  

CD3

Research Areas:  

Inflammation/Immunology

Ciduvectamig is an anti-CD3E/TMEFF2 human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
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Cat. No.: HY-184275
CAS No.: 3126105-55-0
Target:  

Itk ERK

Research Areas:  

Cancer

ITK-IN-7 is a selective ITK inhibitor with an IC50 of 16 nM and a Ki of 0.48 nM. ITK-IN-7 reduces IL-2 secretion levels in T cells and in mouse models stimulated by anti-CD3 monoclonal antibodies. ITK-IN-7 can be used for basic and translational research related to ITK inhibition, such as research on leukemia .
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Cat. No.: HY-180609
CAS No.: 2375043-73-3
Research Areas:  

Inflammation/Immunology

TCR-IN-2 (Compound A-68) is a TCR inhibitor. TCR-IN-2 inhibits the release of IFNγ and IL-2. TCR-IN-2 inhibits the time-dependent phosphorylation of CD3ζ. TCR-IN-2 inhibits TCR-mediated T cell activation, both in response to anti-CD3 antibodies and in response to human cells with unmatched HLA .
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Cat. No.: HY-P991959

Target:  

CTLA-4

Research Areas:  

Inflammation/Immunology Cancer

JMW-3B3 is a humanized IgG1λ monoclonal antibody targeting CTLA-4. JMW-3B3 selectively binds the unique C-terminal sequence of sCTLA-4 to block its immunoregulatory and immunosuppressive activity without cross-reacting with full-length CTLA-4 receptor. JMW-3B3 enhances cytokine profiles in PBMC cultures responding to lupus autoantigen-derived peptides. JMW-3B3 enhances IFN-γ production in anti-CD3 stimulated PBMC from melanoma patients at low anti-CD3 doses. JMW-3B3 can be used for the research of systemic lupus erythematosus and malignant melanoma.
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