253 Results for "

Anti-HIV

" in MedChemExpress (MCE) Product Catalog:
Products (253)

253 Results for "Anti-HIV" in MCE Product Catalog:

38
38 Publications Verification
Cat. No.: HY-10529
CAS No.: 472-15-1
Purity:  99.06%
Synonyms: Lupatic acid; Betulic acid
Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties . Betulinic acid can cross the blood-brain barrier .
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32
32 Cited Publications
Cat. No.: HY-W013332
CAS No.: 6736-58-9
3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 μM; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIV activity.
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32
32 Cited Publications
Cat. No.: HY-W013332A
CAS No.: 86583-19-9
3-Deazaadenosine (hydrochloride) is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 μM; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIV activity.
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17
17 Cited Publications
Cat. No.: HY-17605A
CAS No.: 1807988-02-8
Synonyms: GS-9883 sodium
Target:  

HIV Integrase HIV

Research Areas:  

Infection

Bictegravir sodium is a potent inhibitor of HIV-1 integrase, with an IC50 of 7.5 nM. Bictegravir sodium exhibits potent and selective anti-HIV activity and low cytotoxicity .
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15
15 Cited Publications
Cat. No.: HY-N0056
CAS No.: 2450-53-5
Synonyms: 3,5-Dicaffeoylquinic acid; 3,5-CQA
Isochlorogenic acid A (3,5-Dicaffeoylquinic acid) is a natural phenolic acid with anti-mutagenicity, anti-HBV, anti-HIV, anti-oxidant, anti-bacterial, and anti-inflammatoryy activities .
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13
13 Cited Publications
Cat. No.: HY-12687
CAS No.: 173903-47-4
Purity:  98.10%
Synonyms: TIZ
Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC50 of 0.46μM and 0.15 μM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-κB and the MAPK signaling pathways in LPS-treated macrophage cells .
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9
9 Cited Publications
Cat. No.: HY-116213
CAS No.: 1259330-61-4
Purity:  99.94%
Sparstolonin B acts as a selective TLR2 and TLR4 antagonist and selectively blocks TLR2- and TLR4-mediated inflammatory signaling. Sparstolonin B has anti-HIV and anticancer activities .
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4
4 Cited Publications
Cat. No.: HY-P0052
CAS No.: 159519-65-0
Synonyms: T20; DP178
Target:  

HIV

Research Areas:  

Infection

Enfuvirtide (T20;DP178) is an anti-HIV-1 fusion inhibitor peptide.
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4
4 Cited Publications
Cat. No.: HY-P1034
CAS No.: 106362-34-9
Synonyms: D-Ala-peptide T-amide; Adaptavir
Target:  

CCR HIV

Research Areas:  

Infection Endocrinology

DAPTA is a synthetic peptide, functions as a viral entry inhibitor by targeting selectively CCR5, and shows potent anti-HIV activities.
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4
4 Cited Publications
Cat. No.: HY-P0052A
CAS No.: 914454-00-5
Synonyms: T20 acetate; DP178 acetate
Target:  

HIV

Research Areas:  

Infection

Enfuvirtide (T20; DP178) acetate is an anti-HIV-1 fusion inhibitor peptide.
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4
4 Cited Publications
Cat. No.: HY-N2010
CAS No.: 99-24-1
Synonyms: Gallincin; NSC 363001
Methyl gallate is a plant phenolic with antioxidant, anticancer, and anti-inflammatory activities. Methyl gallate also shows bacterial inhibition activity. Methyl gallate also has anti-HIV-1 and HIV-1 enzyme inhibitory activities.
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4
4 Cited Publications
Cat. No.: HY-B1637
CAS No.: 148-18-5
Synonyms: Sodium diethyldithiocarbamate
Ditiocarb sodium (Sodium diethyldithiocarbamate) is an orally active copper reagent. Ditiocarb sodium exhibits activities such as antioxidation, chelation, anti-tumor effects, immunomodulation, and anti-HIV properties. Ditiocarb sodium can be used in the research of tumors, inflammatory, and immune-related diseases .
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4
4 Cited Publications
Cat. No.: HY-P1102
CAS No.: 368874-34-4
Target:  

CXCR HIV

Research Areas:  

Infection Cancer

TC14012, a serum-stable derivative of T140, is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM. TC14012 is a potent CXCR7 agonist with an EC50 of 350 nM for recruiting β-arrestin 2 to CXCR7. TC14012 has anti-HIV activity and anti-cancer activity .
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4
4 Cited Publications
Cat. No.: HY-B1637A
CAS No.: 148-18-5
Synonyms: Sodium diethyldithiocarbamate,98%
Ditiocarb sodium,98% (Sodium diethyldithiocarbamate,98%) is an orally active copper reagent. Ditiocarb sodium,98% exhibits activities such as antioxidation, chelation, anti-tumor effects, immunomodulation, and anti-HIV properties. Ditiocarb sodium,98% can be used in the research of tumors, inflammatory, and immune-related diseases .
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4
4 Cited Publications
Cat. No.: HY-78726
CAS No.: 226700-79-4
Synonyms: Amprenavir phosphate; GW 433908
Fosamprenavir is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir can be used for the study of human immunodeficiency virus (HIV-1) infection .
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4
4 Cited Publications
Cat. No.: HY-17431
CAS No.: 226700-81-8
Synonyms: GW433908G
Fosamprenavir Calcium Salt (GW433908G) is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir Calcium Salt is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir Calcium Salt can be used for the study of human immunodeficiency virus (HIV-1) infection .
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2
2 Cited Publications
Cat. No.: HY-19149
CAS No.: 139339-45-0
Target:  

HIV Apoptosis

Ro24-7429 is a potent and orally active HIV-1 transactivator protein Tat antagonist. Ro24-7429 is also a runt-related transcription factor 1 (RUNX1) inhibitor. Ro24-7429 has anti-HIV, antifibrotic and anti-inflammatory effects .
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2
2 Cited Publications
Cat. No.: HY-N0858
CAS No.: 62956-48-3
Gomisin G is a lignin from S. chinesis with anti-HIV (EC50 = 0.006 μg/mL), anti-liver cancer and anti-inflammatory activities. Gomisin G has an AKT-cyclin D1 dependent mechanism against triple-negative breast cancer (TNBC) cells through suppressing phosphorylation rather than inducing apoptosis. Gomisin G can inhibit AKT phosphorylation. Gomisin G can cause cell cycle arrest in the G1 phase. Gomisin G can be studied in research for diseases such as HIV, breast and liver cancers .
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2
2 Cited Publications
Cat. No.: HY-119500
CAS No.: 71678-03-0
Purity:  ≥98.0%
Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway. Ilimaquinone can induce vesiculation of the Golgi apparatus . Ilimaquinone exerts anti-HIV, anti-microbial, anti-inflammatory, and effects .
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2
2 Cited Publications
Cat. No.: HY-A0203A
CAS No.: 140207-93-8
Target:  

HIV

Pentosan Polysulfate Sodium is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate Sodium also is a potent and selective anti-HIV agent. Pentosan Polysulfate Sodium is used for the treatment of interstitial cystitis .
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