9 Results for "

Autophagy-IN-5

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "Autophagy-IN-5" in MCE Product Catalog:

Autophagy-IN-5
Autophagy-IN-5
0 Images
Cat. No.: HY-160896
CAS No.: 1262888-20-9
Target:  

Autophagy

Research Areas:  

Inflammation/Immunology Cancer

Autophagy-IN-5 (Compound A9) is an inhibitor for autophagy with an EC50 of 0.736 μM .
loading...
    loading...
View All Sizes
224
Forskolin
Forskolin
0 Images
224 Cited Publications
Cat. No.: HY-15371
CAS No.: 66575-29-9
Purity:  98.95%
Synonyms: Coleonol; ColforsIN; HL 362
Category:  

Labiatae Terpenoids Metabolic Disease Diterpenoids Plants Disease Research Fields Inflammation/Immunology Endocrinology Pueraria montana (Lour.) Merr.

Target:  

Organoid Adenylate Cyclase FXR Autophagy PKC

Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase . Forskolin is also an inducer of intracellular cAMP formation . Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR . Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy .
loading...
    loading...
View All Sizes
Glyburide-d3
Glyburide-d3
0 Images
Cat. No.: HY-15206S1
CAS No.: 1219803-02-7
Purity:  99.24%
Synonyms: Glyburide-d3
Glyburide-d3 is the deuterium labeled Glibenclamide. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity[1]. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR)[3]. Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability[4]. Glibenclamide can induce autophagy[5].
loading...
    loading...
View All Sizes
Forskolin (Standard)
Forskolin (Standard)
0 Images
Cat. No.: HY-15371R
CAS No.: 66575-29-9
Synonyms: Coleonol (Standard); ColforsIN (Standard); HL 362 (Standard)
Category:  

Labiatae Terpenoids Diterpenoids Plants Pueraria montana (Lour.) Merr.

Target:  

Organoid Reference Standards Adenylate Cyclase FXR Autophagy PKC

Forskolin (Standard) is the analytical standard of Forskolin. This product is intended for research and analytical applications. Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase . Forskolin is also an inducer of intracellular cAMP formation . Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR . Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy .
loading...
    loading...
View All Sizes
Forskolin (GMP)
Forskolin (GMP)
0 Images
Cat. No.: HY-15371G
CAS No.: 66575-29-9
Synonyms: Coleonol (GMP); ColforsIN (GMP); HL 362 (GMP)
Forskolin (Coleonol) (GMP) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase . Forskolin (GMP) is also an inducer of intracellular cAMP formation . Forskolin (GMP) induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR . Forskolin (GMP) exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin (GMP) also induces autophagy .
loading...
    loading...
View All Sizes
5-Heptadecylresorcinol
5-Heptadecylresorcinol
0 Images
Cat. No.: HY-N2673
CAS No.: 41442-57-3
Synonyms: 5-n-HeptadecylresorcINol; AR-C17
Category:  

Gramineae Secale cereale Phenols Polyphenols Plants

Target:  

Sirtuin

5-Heptadecylresorcinol (AR-C17), a phenolic lipid component, is also an orally active mitochondrial protector. 5-Heptadecylresorcinol improves mitochondrial function via sirtuin3 signaling pathway, thus alleviates endothelial cell damage and apoptosis. 5-Heptadecylresorcinol induces sirtuin3-mediated autophagy. 5-Heptadecylresorcinol reduces the atherosclerotic plaques in the aortic root region of mice heart. 5-Heptadecylresorcinol can be used for research of atherosclerosis prevention and obesity .
loading...
    loading...
View All Sizes
5-Heptadecylresorcinol (Standard)
5-Heptadecylresorcinol (Standard)
0 Images
Cat. No.: HY-N2673R
CAS No.: 41442-57-3
Synonyms: 5-n-HeptadecylresorcINol (Standard); AR-C17 (Standard)
Category:  

Gramineae Secale cereale Phenols Polyphenols Plants

Target:  

Reference Standards Sirtuin

5-Heptadecylresorcinol (AR-C17), a phenolic lipid component, is also an orally active mitochondrial protector. 5-Heptadecylresorcinol improves mitochondrial function via sirtuin3 signaling pathway, thus alleviates endothelial cell damage and apoptosis. 5-Heptadecylresorcinol induces sirtuin3-mediated autophagy. 5-Heptadecylresorcinol reduces the atherosclerotic plaques in the aortic root region of mice heart. 5-Heptadecylresorcinol can be used for research of atherosclerosis prevention and obesity .
loading...
    loading...
View All Sizes
Autophagy inducer 5
Autophagy inducer 5
0 Images
Cat. No.: HY-159605
Target:  

Autophagy JNK Reactive Oxygen Species (ROS)

Research Areas:  

Cancer

Autophagy inducer 5 (compound 21o) is a potent MCF-7 inhibitor (IC50: 2 μM), and a potential breast cancer inhibitor. Autophagy inducer 5 induces cellular autophagy by activating the ROS/JNK signaling pathway, which increases ROS generation and JNK phosphorylation, exerting cytotoxic effects .
loading...
    loading...
View All Sizes
ATG5/TECAIR-IN-1
ATG5/TECAIR-IN-1
0 Images
Cat. No.: HY-183737
CAS No.: 2841473-83-2
Target:  

Autophagy

Research Areas:  

Infection Cancer

ATG5/TECAIR-IN-1 is a ATG5-TECAIR interaction inhibitor with an IC50 of 20.79 μM. ATG5/TECAIR-IN-1 inhibits autophagy. TG5/TECAIR-IN-1 is applicable to research on modulating protein-protein interactions to intervene in autophagy-related diseases, such as infectious diseases and cancers .
loading...
    loading...
View All Sizes
Assay Types