2. Autophagy
  3. Autophagy
  4. Autophagy-IN-5

Autophagy-IN-5 (Compound A9) is an inhibitor for autophagy with an EC50 of 0.736 μM.

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Autophagy-IN-5

Autophagy-IN-5 Chemical Structure

CAS No. : 1262888-20-9

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
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Autophagy-IN-5 Related Antibodies

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Description

Autophagy-IN-5 (Compound A9) is an inhibitor for autophagy with an EC50 of 0.736 μM[1].

Molecular Weight

287.72

Formula

C15H11ClFN3
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

FC1=CC2=C(NCC3=CC=C(C=C3)Cl)N=CN=C2C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (34.76 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4756 mL 17.3780 mL 34.7560 mL
5 mM 0.6951 mL 3.4756 mL 6.9512 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4756 mL 17.3780 mL 34.7560 mL 86.8900 mL
5 mM 0.6951 mL 3.4756 mL 6.9512 mL 17.3780 mL
10 mM 0.3476 mL 1.7378 mL 3.4756 mL 8.6890 mL
15 mM 0.2317 mL 1.1585 mL 2.3171 mL 5.7927 mL
20 mM 0.1738 mL 0.8689 mL 1.7378 mL 4.3445 mL
25 mM 0.1390 mL 0.6951 mL 1.3902 mL 3.4756 mL
30 mM 0.1159 mL 0.5793 mL 1.1585 mL 2.8963 mL
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Autophagy-IN-5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Autophagy-IN-51262888-20-9Autophagyacute pancreatitisH4-LC3Inhibitorinhibitorinhibit

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