23 Results for "

BEL7402

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "BEL7402" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-107632
CAS No.: 106740-09-4
Purity:  98.08%
GY4137 is a sustained-release H2S donor possessing vasodilatory, antihypertensive, and anti-inflammatory activities. GY4137 can inhibit cell growth, induce apoptosis, and cause cell cycle arrest by blocking the STAT3 pathway, demonstrating potent anticancer activity .
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Cat. No.: HY-N11928
CAS No.: 136040-44-3
Changnanic acid (schisandrin) is a triterpene compound with potential anti-tumor effects. Changnanic acid exhibits moderate cytotoxic activity against human tumor cell lines Bel-7402, MCF-7 and HL-60, with IC50s of 100 μM, 100 μM and 50.51 μM respectively .
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Cat. No.: HY-N7980
CAS No.: 2170211-22-8
Rubipodanone A, a naphthohydroquinone dimer, shows cytotoxicity against A549, BEL-7402, HeLa, HepG2, SGC-7901 and U251 cells. Rubipodanone A also shows obvious activating effect at 20 and 40 μM for NF-κB .
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Cat. No.: HY-177269
CAS No.: 2648988-92-3
Target:  

Arf Family GTPase

Research Areas:  

Cancer

CHNQD-01269, a brefeldin A-cinnamate derivative, is an Arf1 inhibitor. CHNQD-01269 exhibits potent cytotoxic activity against HepG2 and BEL-7402 cells, with IC50 values of 0.29 and 0.84 μM, respectively. CHNQD-01269 is indicated for hepatocellular carcinoma (HCC) research .
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Cat. No.: HY-132972
CAS No.: 2866261-50-7
TrxR-IN-2 is a thioredoxin reductase (TrxR) inhibitor. TrxR-IN-2 increases reactive oxidative species (ROS) levels and decreases mitochondrial transmembrane potential levels. TrxR-IN-2 triggers DNA damage via H2AX regulation, and induces autophagy via LC3, beclin-1, and p62 regulation. TrxR-IN-2 can be used for the research of drug-resistant hepatocellular carcinoma[1].
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Cat. No.: HY-144253
Target:  

Akt ERK

Research Areas:  

Cancer

AKT-IN-11 is one of the most effective antibacterial agents against human hepatoma BEL-7402 cell line with an IC50 value of 1.15μM.
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Cat. No.: HY-N12128
CAS No.: 1418183-25-1
Ophiopogonin R (compound 3) is a steroid saponin. Ophiopogonin R was isolated and purified from natural ophiopogonin. Ophiopogonin R was not cytotoxic to five human tumor cell lines (HepG2, HLE, BEL7402, BEL7403 and Hela) .
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Cat. No.: HY-155695
Target:  

HDAC

Research Areas:  

Cancer

HDAC-IN-61 (compound 12k) is a potent and orally active HDAC inhibitor. HDAC-IN-61 has anticancer active with an IC50 value of 30 nM for Bel-7402 cell. HDAC-IN-61 can be used in research of cancer .
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Cat. No.: HY-N7623
CAS No.: 989-72-0
Target:  

Drug Derivative

Research Areas:  

Cancer

Ursonic acid methyl ester is an esterified derivative of Ursolic acid (HY-N0140). Ursonic acid methyl ester shows growth inhibitory activity against four tumor cell lines, HL-60, BGC, Bel-7402 and Hela with ED50 values of >100 µg/ml .
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Cat. No.: HY-146467
CAS No.: 2413148-58-8
Target:  

Drug Derivative

Research Areas:  

Cancer

Anticancer agent 62 (compound 4c) is a potent anticancer agent. Anticancer agent 62 shows antiproliferative activity in HepG2, Bel-7402 and MCF-7 cancer cells, with IC50 values of 0.019, 0.060 and 0.016 μM, respectively. Anticancer agent 62 shows effective tumor growth inhibition .
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Cat. No.: HY-146466
CAS No.: 2413148-53-3
Target:  

Others

Research Areas:  

Cancer

Anticancer agent 61 (compound 3v) is an orally active and potent anticancer agent. Anticancer agent 61 shows antiproliferative activity in HepG2, Bel-7402 and MCF-7 cancer cells, with IC50 values of 1.12, 1.97 and 1.08 μM, respectively. Anticancer agent 61 shows effective tumor growth inhibition .
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Cat. No.: HY-N12253
CAS No.: 16763-48-7
(19R)-13-Deoxy-19-hydroxyenmein is the parent compound of enmein-type diterpenoid analogs. (19R)-13-Deoxy-19-hydroxyenmein has anti-proliferative activities with IC50 values of 0.41, 0.85, 0.43, 1.89 μM against human cancer cell lines K562, MGC-803, CaEs-17, and Bel-7402, respectively .
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Cat. No.: HY-N7535
CAS No.: 96801-92-2
Chlorovaltrate K is a chlorinated valepotriate with anticancer effects. Chlorovaltrate K shows moderate cytotoxicity against A549, PC-3M, HCT-8 and Bel 7402 cell lines with IC50 values of 2.32-8.26 μM .
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Cat. No.: HY-N13081
CAS No.: 6869-66-5
Category:  

Microorganisms Steroids

Target:  

Others

3-Oxo-cinobufagin (compound 8) is a potential anticancer compound that can be isolated from the broth of M. spinosus by high-performance liquid chromatography. Compared to other isolated compounds, the hydroxyl group at the C-5 position of 3-Oxo-cinobufagin is further oxidized or isomerized, significantly reducing its cytotoxic activity against most cell lines (except HEL), while increasing its activity against the BEL cell line. The IC50 values of 3-Oxo-cinobufagin's cytotoxicity against cancer cells are: 71.3 μM (HepG2), 90.2 μM (SMMC-7221), 0.11 μM (BEL-7402), 72.5 μM (K562), 5.3 μM (HL-60), and 12 nM (HEL) .
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Cat. No.: HY-111243
CAS No.: 873061-79-1
Target:  

HSV

Ganoderone A is a triterpene compound that can be isolated from the fruiting body of Ganoderma pfeifferi and Ganoderma calidophilum. Ganoderone A has antiviral activity against HSV with IC50 value of 0.3 µg/mL. Ganoderone A has potential applications in viral infections and tumors .
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Cat. No.: HY-N16667
CAS No.: 330195-61-4
Cathyanin C (Compound 8) is a flavonoid found in Morus cathayana. Cathyanin C can be used for the research of cancer .
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Cat. No.: HY-N16669
CAS No.: 330195-60-3
Cathyanin B (Compound 7) is a flavonoid found in Morus cathayana. Cathyanin B can be used for the research of cancer, such as lung cancer .
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Cat. No.: HY-N21525
CAS No.: 1454585-35-3
Cronupapin methyl ester is a 2-benzylmalate benzyl ester glucoside found in the tubers of Cremastra appendiculata with IC50 > 50 μM against cancer cells .
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Cat. No.: HY-N21520
CAS No.: 1454585-37-5
4-Methoxy-9,10-dihydrophenanthrene-2,7-di-O-beta-D-glucopyranoside is a glycosidic 9,10-dihydrophenanthrene derivative found in the tubers of Cremastra appendiculata. 4-Methoxy-9,10-dihydrophenanthrene-2,7-di-O-beta-D-glucopyranoside shows in vitro inactivity against human cancer cells .
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