2648988-92-3
Chemical Structure
CHNQD-01269
- CAS No.: 2648988-92-3
- Formula:C27H35NO5
- Molecular Weight:453.57
SMILES: CN(C)C(C=C1)=CC=C1/C=C/C(O[C@H]2[C@@]3([H])[C@@](/C=C/CCC[C@@H](OC(/C=C/2)=O)C)([H])C[C@@H](C3)O)=O
Biological Activity: CHNQD-01269, a brefeldin A-cinnamate derivative, is an Arf1 inhibitor. CHNQD-01269 exhibits potent cytotoxic activity against HepG2 and BEL-7402 cells, with IC50 values of 0.29 and 0.84 μM, respectively. CHNQD-01269 is indicated for hepatocellular carcinoma (HCC) research[1].
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CHNQD-01269 | CHNQD-01269, a brefeldin A-cinnamate derivative, is an Arf1 inhibitor. CHNQD-01269 exhibits potent cytotoxic activity against HepG2 and BEL-7402 cells, with IC50 values of 0.29 and 0.84 μM, respectively. CHNQD-01269 is indicated for hepatocellular carcinoma (HCC) research. | |||||||||||||||||||||
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Keywords