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Cat. No.: HY-111243

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Ganoderone A

Ganoderone A is a triterpene compound that can be isolated from the fruiting body of Ganoderma pfeifferi and Ganoderma calidophilum. Ganoderone A has antiviral activity against HSV with IC₅₀ value of 0.3 µg/mL. Ganoderone A has potential applications in viral infections and tumors.

For research use only. We do not sell to patients.

CAS No.: 873061-79-1
Formula: C₃₀H₄₆O₃
Molecular Weight:454.68

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Ganoderone A Chemical Structure

CAS No.: 873061-79-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

HSV

0.3 μg/mL (IC₅₀)

All HSV Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
K562	IC₅₀	27.7 μM Compound: 19	Cytotoxicity against human K562 cells by MTT method Cytotoxicity against human K562 cells by MTT method	[PMID: 26287401]
MDCK	IC₅₀	0.3 μg/mL Compound: 2, ganoderone A	Antiviral activity against herpes simplex virus 1 infected in MDCK cells Antiviral activity against herpes simplex virus 1 infected in MDCK cells	[PMID: 16378363]
PC-3	IC₅₀	28.5 μM Compound: 19	Cytotoxicity against human PC3 cells by MTT method Cytotoxicity against human PC3 cells by MTT method	[PMID: 26287401]

In Vitro

Ganoderone A exhibits cytotoxic activity on K562, BEL7402 and SGC790 cell lines with IC₅₀ values of 7.62 µM, 6.28 µM and 3.55 µM, respectively^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 873061-79-1
Molecular Weight 454.68
Formula C₃₀H₄₆O₃
SMILES

C[C@]12C3=C(CC[C@@]1([C@@]([H])([C@@H](CC/C=C(CO)\C)C)CC2)C)[C@@]4([C@@](C(C)(C(CC4)=O)C)([H])CC3=O)C
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
- Microorganisms
Ganoderma pfeifferi
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Niedermeyer TH, et al. Antiviral Terpenoid Constituents of Ganoderma pfeifferi. J Nat Prod. 2005 Dec;68(12):1728-31. [Content Brief]

[2]. Huang S Z, et al. Anti-allergic prenylated hydroquinones and alkaloids from the fruiting body of Ganoderma calidophilum[J]. RSC advances, 2016, 6(25): 21139-21147.

[3]. Huang SZ, et al. Lanostane-type triterpenoids from the fruiting body of Ganoderma calidophilum. Phytochemistry. 2017 Nov;143:104-110. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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Ganoderone A

All HSV Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Ganoderone A Related Classifications

HY-111243 Related Classifications