1. NF-κB
  2. NF-κB
  3. Rubipodanone A

Rubipodanone A, a naphthohydroquinone dimer, shows cytotoxicity against A549, BEL-7402, HeLa, HepG2, SGC-7901 and U251 cells. Rubipodanone A also shows obvious activating effect at 20 and 40 μM for NF-κB.

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Rubipodanone A Chemical Structure

Rubipodanone A Chemical Structure

CAS No. : 2170211-22-8

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Description

Rubipodanone A, a naphthohydroquinone dimer, shows cytotoxicity against A549, BEL-7402, HeLa, HepG2, SGC-7901 and U251 cells. Rubipodanone A also shows obvious activating effect at 20 and 40 μM for NF-κB[1].

In Vitro

Rubipodanone A shows cytotoxicity against A549, BEL-7402, HeLa, HepG2, SGC-7901 and U251 cells (IC50=16.77-31.89 μM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

442.46

Formula

C27H22O6

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

C/C(C)=C\C[C@@](C(C1=CC=CC=C21)=O)(C(C(C3=CC=CC=C34)=O)=CC4=O)C(C(OC)=O)=C2O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Purity: ≥99.0%

References
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Rubipodanone A Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Rubipodanone A
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HY-N7980
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