2. NF-κB
  3. NF-κB
  4. Rubipodanone A

Rubipodanone A, a naphthohydroquinone dimer, shows cytotoxicity against A549, BEL-7402, HeLa, HepG2, SGC-7901 and U251 cells. Rubipodanone A also shows obvious activating effect at 20 and 40 μM for NF-κB.

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Rubipodanone A Chemical Structure

Rubipodanone A Chemical Structure

CAS No. : 2170211-22-8

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Based on 1 publication(s) in Google Scholar

Rubipodanone A Related Antibodies

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Description

Rubipodanone A, a naphthohydroquinone dimer, shows cytotoxicity against A549, BEL-7402, HeLa, HepG2, SGC-7901 and U251 cells. Rubipodanone A also shows obvious activating effect at 20 and 40 μM for NF-κB[1].

In Vitro

Rubipodanone A shows cytotoxicity against A549, BEL-7402, HeLa, HepG2, SGC-7901 and U251 cells (IC50=16.77-31.89 μM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Rubipodanone A Related Antibodies
Molecular Weight

442.46

Formula

C27H22O6
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

C/C(C)=C\C[C@@](C(C1=CC=CC=C21)=O)(C(C(C3=CC=CC=C34)=O)=CC4=O)C(C(OC)=O)=C2O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Purity: ≥99.0%

COA (260 KB)

Handling Instructions (2659 KB)
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Rubipodanone A Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rubipodanone A2170211-22-8NF-κBNuclear factor-κBNuclear factor-kappaBnaphthohydroquinonedimercytotoxicityA549BEL-7402HeLaHepG2SGC-7901U251cellsInhibitorinhibitorinhibit

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