1 Result for "

BP-1002

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BP-1002" in MCE Product Catalog:

Cat. No.: HY-188138
Research Areas:  

Cancer

BP1002 is an antisense oligonucleotide targeting BCL-2. BP1002 silences BCL-2 expression by targeting the translation initiation site of Bcl-2 mRNA. Its backbone carries ethoxy modifications, which confer nuclease resistance, reduce off-target effects, and lower toxicity. BP1002 prolongs survival in non-Hodgkin's lymphoma xenograft models. BP1002 can be used in studies of acute myeloid leukemia, aggressive non-Hodgkin's lymphoma, and Venetoclax (HY-15531)-resistant hematological malignancies .
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