Search Result

Results for "

Benzylguanine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (2) Apoptosis (2) Biochemical Assay Reagents (4) DNA/RNA Synthesis (2) Drug Derivative (2) Drug Intermediate (1) Fluorescent Dye (3) Nucleoside Antimetabolite/Analog (1) Reference Standards (1)
By Research Areas:	Cancer (3)
Click Chemistry:	Labeling and Fluorescence Imaging (2) Alkynes (2)

Inhibitors & Agonists

Fluorescent Dyes

Peptides

Natural
Products

Click Chemistry

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-W002585

O6-Benzylguanine 2 Publications Verification	DNA/RNA Synthesis Apoptosis	Cancer
O6-Benzylguanine, a guanine analog, is the DNA repair enzyme O6-alkylguanine-DNA alkyltransferase (MGMT/AGT) inhibitor. O6-Benzylguanine acts as an AGT substrate, which transfers its benzyl group to the AGT cysteine residue, thereby irreversibly inactivating AGT and preventing DNA repair. O6-Benzylguanine induces tumor cell apoptosis. Antineoplastic activity .

HY-151645

Alkyne-SNAP	ADC Linker	Others
Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation .

HY-151646

Alkyne-PEG5-SNAP Alkyne-PEG5-BG	ADC Linker	Others
Alkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group. Alkyne-PEG5-SNAP can alkyne conjugated benzylguanine (BG), the BG moiety reacts specifically and rapidly with SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation . Alkyne-PEG5-SNAP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W002585R

*O6-Benzylguanine* (Standard)**	Reference Standards DNA/RNA Synthesis Apoptosis	Cancer
O6-Benzylguanine, a guanine analog, is the DNA repair enzyme O6-alkylguanine-DNA alkyltransferase (MGMT/AGT) inhibitor. O6-Benzylguanine acts as an AGT substrate, which transfers its benzyl group to the AGT cysteine residue, thereby irreversibly inactivating AGT and preventing DNA repair. O6-Benzylguanine induces tumor cell apoptosis. Antineoplastic activity .

HY-D2994

SPY555-BG SNAP-MaP555	Fluorescent Dye	Others
SPY555-BG (SNAP-MaP555) is the benzylguanine derivative of SPY555 fluorophore. SPY555-BG emits light in the orange part of the UV-ViS spectrum. SPY555-BG is fluorogenic, highly cell permeable and well suited for STED and SIM superresolution imaging. SPY555-BG can be imaged with a standard Cy3 filterset. SPY555-BG can be used for widefield, confocal, SIM or STED imaging in living or fixed cells and tissue .

HY-D2929

BG-JF585 SNAP-JF585	Fluorescent Dye	Others
BG-JF585 is Benzylguanine-conjugated JF585 (HY-131025). Benzylguanine is the substrate for SNAP tags. JF585 is a fluorophore (λabs: 593 nm; λem: 611 nm).

HY-D2933

SNAP-505	Fluorescent Dye	Others
SNAP-505 is a green fluorescent O6 benzylguanine derivative. SNAP-505 labels SNAP-tagged proteins covalently. SNAP-505 can be used to label cells (green) .

HY-W1124386

BG-DBCO SNAP-DBCO	Drug Intermediate Drug Derivative	Cancer
BG-DBCO is a DBCO-conjugated Benzylguanine. BG-DBCO, SNAP-E3 fusion protein and Ligand-N3 form a protein complex. BG-DBCO is conjugated with JQ1-N3-C10 to obtain BG-JQ1. BG-JQ1, administered together with SIAH1-SN mRNA, effectively inhibits the growth of small cell carcinoma of the adrenocortical gland .

HY-N15896

*18:1 PE-PEG2000-Benzylguanine* ammonium**	Biochemical Assay Reagents	Others
18:1 PE-PEG2000-Benzylguanine ammonium is a SNAP-tag reacting lipid.

HY-N15911

*18:1 PE-Benzylguanine* ammonium**	Biochemical Assay Reagents	Others
18:1 PE-Benzylguanine ammonium is a SNAP-tag reacting lipid.

HY-D2925

dTCOBG dTCO-SNAP	Biochemical Assay Reagents	Others
dTCOBG (dTCO-SNAP) is a SNAP-tag reactive benzylguanine (BG) analogue specifically designed for the specific labeling of immune cells. dTCOBG forms a stable thioether bond through the cysteine at the active site of SNAP-tag and O6-benzylguanine, resulting in a covalent linkage. dTCOBG demonstrates unique advantages in the labeling of macrophages derived from ER-HoxB8: it only labels SNAP-tag + macrophages, with no background signal in the control group. dTCOBG can be used for click chemistry labeling .

HY-D2932

BG-Maleimide SNAP-Maleimide	Biochemical Assay Reagents	Others
BG-maleimide is a building block. BG-maleimide allows the attachment of Benzylguanine to thiolcontaining precursors .

HY-D2957

BG-Nor NorBG; SNAP-Nor	Drug Derivative Nucleoside Antimetabolite/Analog	Others
BG-Nor (NorBG) is a Benzylguanine analogue containing Norbornene (HY-W013021). BG-Nor can be converted by cell surface SNAP tags. NorBG can be used for tetrazine-linked labeling of cells via the iEDDA reaction .

Cat. No.	Nombre del producto	Type

HY-D2994

SPY555-BG SNAP-MaP555	Fluorescent Dyes
SPY555-BG (SNAP-MaP555) is the benzylguanine derivative of SPY555 fluorophore. SPY555-BG emits light in the orange part of the UV-ViS spectrum. SPY555-BG is fluorogenic, highly cell permeable and well suited for STED and SIM superresolution imaging. SPY555-BG can be imaged with a standard Cy3 filterset. SPY555-BG can be used for widefield, confocal, SIM or STED imaging in living or fixed cells and tissue .

SPY555-BG

SNAP-MaP555

Fluorescent Dyes

SPY555-BG (SNAP-MaP555) is the benzylguanine derivative of SPY555 fluorophore. SPY555-BG emits light in the orange part of the UV-ViS spectrum. SPY555-BG is fluorogenic, highly cell permeable and well suited for STED and SIM superresolution imaging. SPY555-BG can be imaged with a standard Cy3 filterset. SPY555-BG can be used for widefield, confocal, SIM or STED imaging in living or fixed cells and tissue .

HY-D2929

BG-JF585 SNAP-JF585	Fluorescent Dyes
BG-JF585 is Benzylguanine-conjugated JF585 (HY-131025). Benzylguanine is the substrate for SNAP tags. JF585 is a fluorophore (λabs: 593 nm; λem: 611 nm).

HY-D2933

SNAP-505	Fluorescent Dyes
SNAP-505 is a green fluorescent O6 benzylguanine derivative. SNAP-505 labels SNAP-tagged proteins covalently. SNAP-505 can be used to label cells (green) .

HY-W1124386

BG-DBCO SNAP-DBCO	Fluorescent Dyes
BG-DBCO is a DBCO-conjugated Benzylguanine. BG-DBCO, SNAP-E3 fusion protein and Ligand-N3 form a protein complex. BG-DBCO is conjugated with JQ1-N3-C10 to obtain BG-JQ1. BG-JQ1, administered together with SIAH1-SN mRNA, effectively inhibits the growth of small cell carcinoma of the adrenocortical gland .

HY-D2925

dTCOBG dTCO-SNAP	Fluorescent Dyes
dTCOBG (dTCO-SNAP) is a SNAP-tag reactive benzylguanine (BG) analogue specifically designed for the specific labeling of immune cells. dTCOBG forms a stable thioether bond through the cysteine at the active site of SNAP-tag and O6-benzylguanine, resulting in a covalent linkage. dTCOBG demonstrates unique advantages in the labeling of macrophages derived from ER-HoxB8: it only labels SNAP-tag + macrophages, with no background signal in the control group. dTCOBG can be used for click chemistry labeling .

dTCOBG

dTCO-SNAP

Fluorescent Dyes

dTCOBG (dTCO-SNAP) is a SNAP-tag reactive benzylguanine (BG) analogue specifically designed for the specific labeling of immune cells. dTCOBG forms a stable thioether bond through the cysteine at the active site of SNAP-tag and O6-benzylguanine, resulting in a covalent linkage. dTCOBG demonstrates unique advantages in the labeling of macrophages derived from ER-HoxB8: it only labels SNAP-tag + macrophages, with no background signal in the control group. dTCOBG can be used for click chemistry labeling .

HY-D2932

BG-Maleimide SNAP-Maleimide	Fluorescent Dyes
BG-maleimide is a building block. BG-maleimide allows the attachment of Benzylguanine to thiolcontaining precursors .

HY-D2957

BG-Nor NorBG; SNAP-Nor	Fluorescent Dyes
BG-Nor (NorBG) is a Benzylguanine analogue containing Norbornene (HY-W013021). BG-Nor can be converted by cell surface SNAP tags. NorBG can be used for tetrazine-linked labeling of cells via the iEDDA reaction .

Cat. No.	Nombre del producto	Target	Research Area

HY-P3983

[Cys(Bzl)84] CD (81-92)	Peptides	Others
[Cys(Bzl)84] CD (81-92) is an acidic peptide. [Cys(Bzl)84] CD (81-92) can be sequencing by negative ion postsource decay (PSD) spectra .

*18:1 PE-PEG2000-Benzylguanine* ammonium**	Lipid	Biochemical Assay Reagents
18:1 PE-PEG2000-Benzylguanine ammonium is a SNAP-tag reacting lipid.

*18:1 PE-Benzylguanine* ammonium**	Lipid	Biochemical Assay Reagents
18:1 PE-Benzylguanine ammonium is a SNAP-tag reacting lipid.

Cat. No.	Nombre del producto		Classification

HY-151645

Alkyne-SNAP		Alkynes Labeling and Fluorescence Imaging
Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation .

HY-151646

Alkyne-PEG5-SNAP Alkyne-PEG5-BG		Alkynes Labeling and Fluorescence Imaging
Alkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group. Alkyne-PEG5-SNAP can alkyne conjugated benzylguanine (BG), the BG moiety reacts specifically and rapidly with SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation . Alkyne-PEG5-SNAP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Consulta en línea

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Saludo			Country or Region *
Nombre del solicitante *			Nombre de la Organizaciòn *
Department *
Direcciòn del E-mail *			Nombre del producto *
Cat. No.			Requested quantity *
Número de teléfono *
Observaciones

Consulta en línea

Inquiry Information

Nombre del producto:
Cat. No.:
Cantidad:
MCE Japan Authorized Agent:

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

We use cookies

MedChemExpress values your privacy and your trust is important to us. We use cookies to enhance your website experience. Some cookies are necessary to run the website. Privacy and Cookie Policy

Name
E-mail *

	Sorry, but the email address you supplied was invalid.

Benzylguanine

Inhibitors & Agonists

Fluorescent Dyes

Peptides

NaturalProducts

Click Chemistry

Natural
Products