1 Result for "

Bromosporine

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Bromosporine" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-15815
CAS No.: 1619994-69-2
Purity:  99.89%
Research Areas:  

Cancer

Bromosporine, a chemical probe, is a potent BET inhibitor with an IC50 value of 2.1 μM for PCAF. Bromosporine can arrest cell cycle and induce apoptosis in cancer cells. Bromosporine exhibits excellent antitumor activity in xenograft mice model when combined with 5-Fluorouracil (HY-90006). Bromosporine can increase CDK9 T-loop phosphorylation in HIV-1 latency models, resulting the protection of reactivate HIV-1 replication from latency. Bromosporine can be used to research colorectal cancer, acute myeloid leukemia (AML) and AIDS .
loading...
    loading...