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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
Bub1 kinase
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "Bub1 kinase" in MCE Product Catalog:
19
19 Publications Verification
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Research Areas:
BAY-1816032, a chemical probe, is a potent and oral available BUB1 (budding uninhibited by benzimidazoles 1) kinase inhibitor with an IC50 of 7 nM.
4
4 Cited Publications
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2OH-BNPP1 is an inhibitor of BUB1 kinase, a Ser/Thr kinase, used for the treatment of cancer.
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2 Cited Publications
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BAY-524 is a potent Bub1 kinase inhibitor. BAY-524 inhibits the recombinant catalytic domain of human Bub1 with an IC50 of 450 nM. BAY-524 can be used for the research of anti-cancer in combination with other agents .
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BAY-320 is a selective and ATP-competitive Bub1 inhibitor that inhibits the kinase activity of Bub1 with an IC50 of 680 nM. BAY-320 inhibits endogenous Bub1-mediated Sgo1 localization. BAY-320 affects cellular mitotic chromosome arrangement and spindle assembly. BAY-320 inhibits cell proliferation. BAY-320 can be used in the study of cancer such as ovarian cancer and cervical cancer .
Cat. No.: HY-161865
Antitumor agent-180 (Compound 13a) is an inhibitor for BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B). Antitumor agent-180 inhibits the proliferation of ccRCC cell Caki-1 with IC50 of 2.047 µM. Antitumor agent-180 induces necrosis and apoptosis in Caki-1 .
DB-0646 is a multi-target PROTAC degrader that degrades over 125 distinct kinases in various cell lines, with its degradation process dependent on the activity of p97. DB-0646 induces ubiquitination and degradation of GCK, BUB1 and YES1 .
Cat. No.: HY-104001R
CAS No.: 1445830-39-6
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BAY-524 (Standard) is the analytical standard of BAY-524 (HY-104001). This product is intended for research and analytical applications. BAY-524 is a potent Bub1 kinase inhibitor. BAY-524 inhibits the recombinant catalytic domain of human Bub1 with an IC50 of 450 nM. BAY-524 can be used for the research of anti-cancer in combination with other agents .
Cat. No.: HY-P702928
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Bub1; Budding Uninhibited By Benzimidazoles 1 (Yeast Homolog); Prev. Bub1L; Bub1 Budding Uninhibited By Benzimidazoles 1 Homolog; HBub1; Budding Uninhibited By Benzimidazoles 1 Homolog; Bub1A; Putative Serine/Threonine-Protein kinase; Mitotic Checkpoint S
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-102081R
CAS No.: 833481-73-5
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2OH-BNPP1 (Standard) is the analytical standard of 2OH-BNPP1 (HY-102081). This product is intended for research and analytical applications. 2OH-BNPP1 is an inhibitor of BUB1 kinase, a Ser/Thr kinase, used for the treatment of cancer.
Cat. No.: HY-103020R
CAS No.: 1891087-61-8
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BAY-1816032 (Standard) is the analytical standard of BAY-1816032 (HY-103020). This product is intended for research and analytical applications. BAY-1816032, a chemical probe, is a potent and oral available BUB1 (budding uninhibited by benzimidazoles 1) kinase inhibitor with an IC50 of 7 nM.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
