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BAY-524 

Cat. No.: HY-104001
Handling Instructions

BAY-524 is a Bub1 inhibitor, with an IC50 of 450 nM for human Bub1 in the presence of 2 mM ATP.

For research use only. We do not sell to patients.

BAY-524 Chemical Structure

BAY-524 Chemical Structure

CAS No. : 1445830-39-6

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

BAY-524 is a Bub1 inhibitor, with an IC50 of 450 nM for human Bub1 in the presence of 2 mM ATP.

IC50 & Target

IC50: 450 nM (human Bub1, 2 mM ATP)[1]

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0726 mL 10.3631 mL 20.7262 mL
5 mM 0.4145 mL 2.0726 mL 4.1452 mL
10 mM 0.2073 mL 1.0363 mL 2.0726 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

482.48

Formula

C₂₄H₂₄F₂N₆O₃

CAS No.

1445830-39-6

SMILES

COC1=CN=C(C2=NN(CC3=C(F)C=C(OCC)C=C3F)C(OC)=C2C)N=C1NC4=CC=NC=C4

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
BAY-524
Cat. No.:
HY-104001
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BAY-524

Cat. No.: HY-104001