1 Result for "

COX-2/15-LOX-IN-7

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "COX-2/15-LOX-IN-7" in MCE Product Catalog:

Cat. No.: HY-179021
CAS No.: 1860810-23-6
Target:  

COX Lipoxygenase

Research Areas:  

Cancer

COX-2/15-LOX-IN-7 is a potent, selective and orally active dual inhibitor of COX-2 and 15-LOX with IC50 values of 0.022 and 1.19 μM. COX-2/15-LOX-IN-7 also inhibits COX-1 with an IC50 value of 28.081μM. COX-2/15-LOX-IN-7 has low cytotoxicity against human colorectal cancer HT-29 and HCT116 cell lines (IC50 >100 μM for both). COX-2/15-LOX-IN-7 exhibits non-ulcerogenic performance. COX-2/15-LOX-IN-7 can be used for the research of cancer .
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